Novel heteroaromatic C-H insertion of alkylidenecarbenes. A new entry to furopyridine synthesis

被引：33

作者：

Kitamura, T ^{[1
]}

Tsuda, K ^{[1
]}

Fujiwara, Y ^{[1
]}

机构：

[1] Kyushu Univ, Grad Sch Engn, Dept Chem & Biochem, Fukuoka 8128581, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(98)01034-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of alkynyl(phenyl)iodonium tosylates with 4-hydroxypyridine and 3-hydroxypyridine in the presence of potassium tert-butoxide undergoes a novel heteroaromatic C-H insertion of alkylidenecarbenes generated in situ to give the corresponding furopyridine derivatives. The heteroaromatic C-H insertion shows an extremely high selectivity compared with the possible aliphatic C-H insertion. This process is also applied to furoquinoline synthesis. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5375 / 5376

页数：2

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