Probing the binding affinity of small-molecule natural products to the G-quadruplex in C-myc oncogene by electrospray ionization mass spectrometry

被引：15

作者：

Liu, Yiquan ^{[1
]}

Zheng, Bo ^{[1
]}

Xu, Xiaojie ^{[1
]}

Yuan, Gu ^{[1
]}

机构：

[1] Peking Univ, Beijing Natl Lab Mol Sci, Key Lab Bioorgan Chem & Mol Engn Minist Educ, Dept Chem Biol,Coll Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 2010年 / 24卷 / 20期

关键词：

PROMOTER REGION; RECOGNITION; TETRANDRINE; TARGET; DNA; SPECTROSCOPY; ONCOPROTEIN; CONVERSION; INHIBITOR; CATIONS;

D O I：

10.1002/rcm.4730

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：3072 / 3075

页数：4

共 41 条

[21] Stabilization of G-Quadruplex DNA with Platinum(II) Schiff Base Complexes: Luminescent Probe and Down-Regulation of c-myc Oncogene Expression [J].

Wu, Peng ;

Ma, Dik-Lung ;

Leung, Chung-Hang ;

Yan, Siu-Cheong ;

Zhu, Nianyong ;

Abagyan, R. ;

Che, Chi-Ming .

CHEMISTRY-A EUROPEAN JOURNAL, 2009, 15 (47) :13008-13021

[22] Selective recognition of c-myc promoter G-quadruplex and down-regulation of oncogene c-myc transcription in human cancer cells by 3,8a-disubstituted indolizinone [J].

Yang, Fengmin ;

Sun, Xin ;

Wang, Lixia ;

Li, Qian ;

Guan, Aijiao ;

Shen, Gang ;

Tang, Yalin .

RSC ADVANCES, 2017, 7 (82) :51965-51969

[23] Inducement of G-Quadruplex DNA Forming and Down-Regulation of Oncogene C-MYC by Bile Acid-Amino Acid ConjugateBAA [J].

Tian, Mingyue ;

Zhang, Xiufeng ;

Li, Yan ;

Ju, Yong ;

Xiang, Junfeng ;

Zhao, Changqi ;

Tang, Yalin .

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2010, 29 (03) :190-199

[24] Probing ligand and cation binding sites in G-quadruplex nucleic acids by mass spectrometry and electron photodetachment dissociation sequencing [J].

Paul, Dababrata ;

Marchand, Adrien ;

Verga, Daniela ;

Teulade-Fichou, Marie-Paule ;

Bombard, Sophie ;

Rosu, Frederic ;

Gabelica, Valerie .

ANALYST, 2019, 144 (11) :3518-3524

[25] Exploring the Parallel G-Quadruplex Nucleic Acid World: A Spectroscopic and Computational Investigation on the Binding of the c-myc Oncogene NHE III1 Region by the Phytochemical Polydatin [J].

Greco, Francesca ;

Musumeci, Domenica ;

Borbone, Nicola ;

Falanga, Andrea Patrizia ;

Terracciano, Monica ;

Piccialli, Ilaria ;

Roviello, Giovanni Nicola ;

Oliviero, Giorgia .

MOLECULES, 2022, 27 (09)

[26] Biophysical Studies of the Structure, Stability, and Ligand Binding Properties of G-Quadruplex DNA: Thoughts and Comparisons of the K-ras, c-MYC, and Bcl-2 Oncogene Promoter Sequence Quadruplexes [J].

Dettler, Jamie M. ;

Lewis, Edwin A. .

FRONTIERS IN NUCLEIC ACIDS, 2011, 1082 :33-50

[27] Deciphering Binding Potential of Naphthalimide-Coumarin Conjugate with c-MYC G-Quadruplex for Developing Anticancer Agents: A Spectroscopic and Molecular Modeling Approach [J].

Gupta, Saurabh ;

Luxami, Vijay ;

Paul, Kamaldeep .

ACS APPLIED BIO MATERIALS, 2025, 8 (02) :1077-1096

[28] Insight into Stabilization of G-Quadruplex in c-MYC Region with Phenanthroimidazoisoindol-Acrylates and their Binding Behaviour towards Human Serum Albumin [J].

Thakur, Rekha ;

Luxami, Vijay ;

Paul, Kamaldeep .

CHEMMEDCHEM, 2025, 20 (06)

[29] Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC Promoter [J].

Gallo, Angelo ;

Lo Sterzo, Carlo ;

Mori, Mirko ;

Di Matteo, Adele ;

Bertini, Ivano ;

Banci, Lucia ;

Brunori, Maurizio ;

Federici, Luca .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (32) :26539-26548

[30] Using UV-Vis Titration to Elucidate Novel Epigallocatechin Gallate (EGCG)-Induced Binding of the c-MYC G-Quadruplex [J].

Tang, Justin .

PHARMACEUTICALS, 2025, 18 (05)

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