Use of antimicrobials in Chilean Salmon farming: Facts, myths and perspectives

被引:25
作者
Avendano-Herrera, Ruben [1 ,2 ,3 ]
Mancilla, Marcos [4 ]
Miranda, Claudio D. [5 ,6 ]
机构
[1] Univ Andres Bello, Fac Ciencias Vida, Lab Patol Organismos Acuat & Biotecnol Acicola, Vina Del Mar, Chile
[2] Univ Andres Bello, Ctr FONDAP, Interdisciplinary Ctr Aquaculture Res INCAR, Vina Del Mar, Chile
[3] Univ Andres Bello, Ctr Invest Marina Quintay CIMARQ, Valparaiso, Chile
[4] ADL Diagnost Chile, Lab Diagnost & Biotecnol, Puerto Montt, Chile
[5] Univ Catolica Norte, Dept Acuicultura, Lab Patobiol Acuat, Coquimbo 1281, Chile
[6] Univ Catolica Norte, Ctr AquaPacifico, Coquimbo, Chile
关键词
antibiotic; antimicrobial resistance; antimicrobial; ARGs; Chile; one health; Piscirickettsia salmonis; salmon farming; RICKETTSIA-LIKE ORGANISM; PISCIRICKETTSIA-SALMONIS; ANTIBIOTIC-RESISTANCE; ATLANTIC SALMON; QUINOLONE RESISTANCE; ESCHERICHIA-COLI; MARINE-BACTERIA; RAINBOW-TROUT; PUBLIC-HEALTH; COHO SALMON;
D O I
10.1111/raq.12702
中图分类号
S9 [水产、渔业];
学科分类号
0908 ;
摘要
Chile is the second largest producer of salmon (only behind Norway), and high amounts of antimicrobials are used during the marine stage, mainly florfenicol. Intensive antimicrobials use is a relevant concern, prompting the urgent need for use reduction and advancements towards more restricted, efficient application. This review describes the historic and current use of antimicrobials in Chilean salmonid farming. Further covered is the experimental evidence reported to date, thus providing a clearer understanding for the pathogenic nature of Piscirickettsia salmonis-the most important bacterial pathogen and the main target of antimicrobials used in the Chilean industry. This review also assesses research exploring the impacts of antimicrobial treatment on the environment, as well as investigations on the antibiotic susceptibility of salmonid pathogens. This review of the scientific literature contributes to a more unbiased appraisal of the current situation in Chile. Unfortunately, various previous reports dealing with/on the antimicrobial use in the Chilean salmon farming industry have been arrived to insufficiently supported conclusions, thus the present review aims to clarify outdated or poorly substantiated information and assumptions in existing literature. The consequences of antimicrobials in fish farming are covered by this review, which is particularly relevant considering potential impacts on aquatic environments. Focus is given to the selection and spread of drug-resistant bacteria and associated resistance-encoding genes. Finally, herein are provided several recommendations from a One Health perspective for decreasing amounts of used antimicrobials, effectively controlling primary bacterial fish pathogens, developing proper prevention strategies and reducing the dissemination of antimicrobial resistance.
引用
收藏
页码:89 / 111
页数:23
相关论文
共 151 条
[1]  
Ahman J., 2020, CLIN MICROBIOL INFEC, V26
[2]   Mechanism of Quinolone Action and Resistance [J].
Aldred, Katie J. ;
Kerns, Robert J. ;
Osheroff, Neil .
BIOCHEMISTRY, 2014, 53 (10) :1565-1574
[3]   A functional ferric uptake regulator (Fur) protein in the fish pathogen Piscirickettsia salmonis [J].
Almarza, Oscar ;
Valderrama, Katherine ;
Ayala, Manuel ;
Segovia, Cristopher ;
Santander, Javier .
INTERNATIONAL MICROBIOLOGY, 2016, 19 (01) :49-55
[4]   Experimental infection and horizontal transmission of Piscirickettsia salmonis in freshwater-raised Atlantic salmon, Salmo salar L. [J].
Almendras, FE ;
Fuentealba, IC ;
Jones, SRM ;
Markham, F ;
Spangler, E .
JOURNAL OF FISH DISEASES, 1997, 20 (06) :409-418
[5]   Understanding human health risks caused by antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARG) in water environments: Current knowledge and questions to be answered [J].
Amarasiri, Mohan ;
Sano, Daisuke ;
Suzuki, Satoru .
CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY, 2020, 50 (19) :2016-2059
[6]   Horizontal gene exchange in environmental microbiota [J].
Aminov, Rustam I. .
FRONTIERS IN MICROBIOLOGY, 2011, 2
[7]   Antibiotic resistance and its cost: is it possible to reverse resistance? [J].
Andersson, Dan I. ;
Hughes, Diarmaid .
NATURE REVIEWS MICROBIOLOGY, 2010, 8 (04) :260-271
[8]   Salmon aquaculture, Piscirickettsia salmonis virulence, and one health: Dealing with harmful synergies between heavy antimicrobial use and piscine and human health comment on Cabello and Godfrey (2019) [J].
Avendano-Herrera, Ruben .
AQUACULTURE, 2021, 532
[9]   Proper antibiotics use in the Chilean salmon industry: Policy and technology bottlenecks [J].
Avendano-Herrera, Ruben .
AQUACULTURE, 2018, 495 :803-805
[10]   Antibiotics and antibiotic resistance in water environments [J].
Baquero, Fernando ;
Martinez, Jose-Luis ;
Canton, Rafael .
CURRENT OPINION IN BIOTECHNOLOGY, 2008, 19 (03) :260-265