Trichloroisocyanuric/TEMPO oxidation of alcohols under mild conditions: A close investigation

被引：153

作者：

De Luca, L ^{[1
]}

Giacomelli, G ^{[1
]}

Masala, S ^{[1
]}

Porcheddu, A ^{[1
]}

机构：

[1] Univ Studi Sassari, Dipartimento Chim, I-07100 Sassari, Italy

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 68卷 / 12期

关键词：

D O I：

10.1021/jo034276b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient oxidation of primary alcohols to the corresponding carboxylic acids can be carried out at room temperature and in acetone/water, using trichloroisocyanuric acid (TCCA) in the presence of catalytic TEMPO. The mild conditions of this procedure and the total absence of any transition metal make this reaction suitable for safe laboratory use. A possible mechanism is presented and discussed.

引用

页码：4999 / 5001

页数：3

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