Gold nanoparticle platforms as drug and biomacromolecule delivery systems

被引：385
|
作者：
Duncan, Bradley [1 ]
Kim, Chaekyu [1 ]
Rotello, Vincent M. [1 ]
机构：
[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA
来源：
JOURNAL OF CONTROLLED RELEASE | 2010年 / 148卷 / 01期
关键词：
Nanoparticles; Gold; Drug delivery; SELF-ASSEMBLED MONOLAYERS; CELLULAR UPTAKE; MESOPOROUS SILICA; NITRIC-OXIDE; RELEASE; GLUTATHIONE; SURFACE; SIZE; ACTIVATION; DENDRIMERS;
D O I：
10.1016/j.jconrel.2010.06.004
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Gold nanoparticles (AuNPs) are a suitable platform for development of efficient delivery systems. AuNPs can be easily synthesized, functionalized, and are biocompatible. The tunability of the AuNP monolayer allows for complete control of surface properties for targeting and stability/release using these nanocarriers. This review will discuss several delivery strategies utilizing AuNPs. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码：122 / 127
页数：6
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