Violacein:: properties and biological activities

被引:147
作者
Duran, Nelson [1 ]
Justo, Giselle Z. [3 ]
Ferreira, Carmen V. [4 ]
Melon, Patricia S. [5 ]
Cordi, Livia [2 ]
Martins, Dorival [1 ,2 ]
机构
[1] Univ Estadual Campinas, Inst Quim, Lab Quim Biol, BR-13083970 Campinas, SP, Brazil
[2] Univ Mogi Das Cruzes, Nucl Ciencias Ambientais, Mogi Das Cruzes, SP, Brazil
[3] Univ Fed Sao Paulo, Dept Bioquim, BR-04044020 Sao Paulo, Brazil
[4] Univ Estadual Campinas, Inst Biol, Dept Bioquim, Lab Transducao Sinal, BR-13083970 Campinas, SP, Brazil
[5] Univ Estadual Campinas, Inst Biol, Dept Bioquim, Lab Cultura Celulas & Biofarm, BR-13083970 Campinas, SP, Brazil
关键词
D O I
10.1042/BA20070115
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The violet pigment violacein is an indole derivative, isolated mainly from bacteria of the genus Chromobacterium, which exhibits important antitumoural, antimicrobial and antiparasitary properties. Furthermore, the formulation of violacein in different polymeric carriers developed so far offers alternative approaches to overcoming physiological barriers and undesirable physicochemical properties in vivo, thus improving its efficacy.
引用
收藏
页码:127 / 133
页数:7
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