Systemic treatment of metastatic breast cancer

被引:6
作者
Johnston, SRD [1 ]
机构
[1] Royal Marsden Hosp, London SW3 6JJ, England
[2] Inst Canc Res, London SW3 6JJ, England
来源
HOSPITAL MEDICINE | 2001年 / 62卷 / 05期
关键词
D O I
10.12968/hosp.2001.62.5.1573
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This article reviews recent advances in the treatment of metastatic breast cancer in particular the results of randomized controlled phase III clinical trials. These have led to the evidence-based introduction of several new drugs including aromatase inhibitors, taxanes and bisphosphonates, some of which have been shown to impact on overall survival.
引用
收藏
页码:289 / 295
页数:7
相关论文
共 47 条
[1]  
BAUM M, 1980, BREAST CANCER EXPT C, P223
[2]  
BIGANZOLI L, 2000, P AN M AM SOC CLIN, V19, pA73
[3]   Initial paclitaxel improves outcome compared with CMFP combination chemotherapy as front-line therapy in untreated metastatic breast cancer [J].
Bishop, JF ;
Dewar, J ;
Toner, GC ;
Smith, J ;
Tattersall, MHN ;
Olver, IN ;
Ackland, S ;
Kennedy, I ;
Goldstein, D ;
Gurney, H ;
Walpole, E ;
Levi, J ;
Stephenson, J ;
Canetta, R .
JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (08) :2355-2364
[4]  
Blamey R, 1999, EUR J SURG ONCOL, V25, P3
[5]   Anastrozole versus tamoxifen as first-line therapy for advanced breast cancer in 668 postmenopausal women:: Results of the tamoxifen or arimidex randomized group efficacy and tolerability study [J].
Bonneterre, J ;
Thürlimann, B ;
Robertson, JFR ;
Krzakowski, M ;
Mauriac, L ;
Koralewski, P ;
Vergote, I ;
Webster, A ;
Steinberg, M ;
von Euler, M .
JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (22) :3748-3757
[6]  
BONNETERRE J, 1997, P AN M AM SOC CLIN, V16, pA564
[7]   Anastrozole, a potent and selective aromatase inhibitor, versus megestrol acetate in postmenopausal women with advanced breast cancer: Results of overview analysis of two phase III trials [J].
Buzdar, A ;
Jonat, W ;
Howell, A ;
Jones, SE ;
Blomqvist, C ;
Vogel, CL ;
Eiermann, W ;
Wolter, JM ;
Azab, M ;
Webster, A ;
Plourde, PV .
JOURNAL OF CLINICAL ONCOLOGY, 1996, 14 (07) :2000-2011
[8]  
BUZDAR A, 2000, P AN M AM SOC CLIN, V19, pA154
[9]   Second-line chemotherapy for metastatic breast cancer including quality of life issues [J].
Buzdar, AU ;
Hortobagyi, GN ;
Frye, D ;
Valero, V .
BREAST, 1996, 5 (04) :312-317
[10]  
Buzdar AU, 1998, CANCER-AM CANCER SOC, V83, P1142, DOI 10.1002/(SICI)1097-0142(19980915)83:6<1142::AID-CNCR13>3.3.CO