Pathogenicity of H5N8 virus in chickens from Korea in 2014

被引：19

作者：

Song, Byung-Min ^{[1
]}

Kang, Hyun-Mi ^{[1
]}

Lee, Eun-Kyoung ^{[1
]}

Jeong, Jipseol ^{[1
]}

Kang, Yeojin ^{[1
]}

Lee, Hee-Soo ^{[1
]}

Lee, Youn-Jeong ^{[1
]}

机构：

[1] Anim & Plant Quarantine Agcy, Div Avian Dis, Anyang 430757, South Korea

来源：

JOURNAL OF VETERINARY SCIENCE | 2015年 / 16卷 / 02期

关键词：

chicken; H5N8; highly pathogenic avian influenza; pathogenicity; AVIAN INFLUENZA-VIRUS; SOUTH-KOREA; DOMESTIC POULTRY; MIGRATORY BIRDS; WILD BIRDS; DUCKS; OUTBREAKS;

D O I：

10.4142/jvs.2015.16.2.237

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

In 2014, two genetically distinct H5N8 highly pathogenic avian influenza (HPAI) viruses were isolated from poultry and wild birds in Korea. The intravenous pathogenicity indices for the two representative viruses were both 3.0. Mortality of chickens intranasally inoculated with the two H5N8 viruses was 100% with a mean death times of 2.5 and 4.5 days. Mortality rates of the contact groups for the two H5N8 viruses were 33.3% and 66.6%. Our study showed that transmissibility of the novel H5N8 viruses was different from that of previously identified H5N1 HPAI viruses, possibly due to genetic changes.

引用

页码：237 / 240

页数：4

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