Metal-Free Aerobic Sulfenyllactonization of Unsaturated Carboxylic Acids with Thiols Using Air as Sole Oxidant

被引：3
|
作者：
Xiong, Yan-Shi [1 ]
Yu, Yang [1 ]
You, Yi-Peng [1 ]
Weng, Jiang [1 ]
Lu, Gui [1 ]
机构：
[1] Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab Chiral Mol & Drug Discover, Guangzhou 510006, Peoples R China
来源：
CHEMISTRYSELECT | 2020年 / 5卷 / 25期
基金：
中国国家自然科学基金;
关键词：
Metal-free; Sulfenyllactonization; Radical; Difunctionalization; Carboxylic acids; ELECTROCATALYTIC APPROACH; CARBONYL-COMPOUNDS; ALKENES; PHOTOREDOX; STYRENES; OXYGEN; DIFUNCTIONALIZATION; BROMOLACTONIZATION; FUNCTIONALIZATION; CYCLIZATION;
D O I：
10.1002/slct.202000542
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A metal-free aerobic sulfenyllactonization of unsaturated carboxylic acids with thiols has been disclosed. This method proceeded with air as the sole oxidant, without any metal catalyst, which provides an efficient access to a wide range of sulfenylated lactones with moderate to good yields. The operational simplicity, high atom efficiency, scalability and the use of bio-based green solvent under mild conditions are the attractive features of this methodology.
引用
收藏
页码：7382 / 7386
页数：5
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