Gold, Silver, and Palladium Nanoparticles: A Chemical Tool for Biomedical Applications

被引:191
作者
Yaqoob, Sundas Bahar [1 ]
Adnan, Rohana [2 ]
Rameez Khan, Raja Muhammad [3 ]
Rashid, Mohammad [2 ]
机构
[1] Mirpur Univ Sci & Technol Mirpur, Dept Zool, Mirpur, Pakistan
[2] Univ Sains Malaysia, Sch Chem Sci, George Town, Malaysia
[3] Mirpur Univ Sci & Technol Mirpur, Dept Chem, Mirpur, Pakistan
来源
FRONTIERS IN CHEMISTRY | 2020年 / 8卷
关键词
nanoparticles; gold; silver; palladium; toxicity mechanism; physico-chemical toxicity; SURFACE-PLASMON RESONANCE; POLY(BETA-AMINO ESTER) NANOPARTICLES; ANTIBACTERIAL ACTIVITY; IN-VITRO; GREEN SYNTHESIS; TARGETED DELIVERY; PD NANOPARTICLES; PLANT-EXTRACT; CANCER; TOXICITY;
D O I
10.3389/fchem.2020.00376
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Herein, the role of metal-based nanoparticles (NPs) in biomedical analysis and the treatment of critical deceases been highlighted. In the world of nanotechnology, noble elements such as the gold/silver/palladium (Au/Ag/Pd) NPs are the most promising emerging trend to design bioengineering materials that could to be employed as modern diagnostic tools and devices to combat serious diseases. NPs are considered a powerful and advanced chemical tool to diagnose and to cure critical ailments such as HIV, cancer, and other types of infectious illnesses. The treatment of cancer is the most significant application of nanotechnology which is based on premature tumor detection and analysis of cancer cells through Nano-devices. The fascinating characteristic properties of NPs-such as high surface area, high surface Plasmon resonance, multi-functionalization, highly stable nature, and easy processing-make them more prolific for nanotechnology. In this review article, the multifunctional roles of Au/Ag/Pd NPs in the field of medical science, the physicochemical toxicity dependent properties, and the interaction mechanism is highlighted. Due to the cytotoxicity of Ag/Au/Pd NPs, the conclusion and future remarks emphasize the need for further research to minimize the toxicity of NPs in the bio-medicinal field.
引用
收藏
页数:15
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