Effects of Estradiol on Expression of Estrogen Receptor and Collagen mRNAs in Chick Skin

被引：2

作者：

Nishimura, Shotaro ^{[1
]}

Arai, Sayaka ^{[2
]}

Ohtani, Mizuki ^{[2
]}

Shimomura, Yuri ^{[2
]}

Tabata, Shoji ^{[1
]}

机构：

[1] Kyushu Univ, Fac Agr, Fukuoka 8190395, Japan

[2] Kyushu Univ, Grad Sch Bioresource & Bioenvironm Sci, Fukuoka 8190395, Japan

来源：

JOURNAL OF POULTRY SCIENCE | 2022年 / 59卷 / 02期

关键词：

chicken; collagen; estradiol; estrogen receptor; skin; BIOSYNTHESIS; MORPHOLOGY; PATCH; SEX;

D O I：

10.2141/jpsa.0210093

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Skin thickness and strength differ between male and female chickens. This study aimed to clarify the effects of estradiol on the expression of estrogen receptors and collagen mRNA in chicken skin. Estradiol was administered to male chicks for 3 weeks, then ciyosections of skin collected from the cervical, thoracic, dorsal, and pelvic limb regions were stained with hematoxylin and eosin, and dermal thickness was measured. Estrogen receptor and collagen mRNA expression was assessed using real-time RT-PCR, and collagen contents were determined. Estradiol did not alter dermal thickness or the collagen content of the skin from any tested region. Among the estrogen receptors, significantly more ESR1 mRNA was expressed in the thoracic skin of chicks administered with estradiol compared with vehicle (control), and in the thoracic skin compared with skin from other regions within each group. Estradiol did not affect ESR2, GPER, and COL1A1 mRNA expression. These results suggested that estradiol stimulates ESR1 expression in thoracic skin, but does not affect collagen synthesis in skin from any other region of male chicks.

引用

页码：162 / 167

页数：6

共 27 条

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