Electrochemical Aerobic Oxidative Cleavage of (sp3)C-C(sp3)/H Bonds in Alkylarenes

被引：10
作者：
Shen, Tong [1 ,2 ]
Liu, Shuai [2 ]
Zhao, Jianyou [1 ]
Wang, Nengyong [1 ]
Yang, Le [1 ]
Wu, Jintao [1 ]
Shen, Xu [1 ]
Liu, Zhong-Quan [1 ]
机构：
[1] Nanjing Univ Chinese Med, Coll Pharm, Jiangsu Collaborat Innovat Ctr Chinese Med Resour, Nanjing 210023, Peoples R China
[2] Univ Bordeaux, Inst Mol Sci, F-33405 Talence, France
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2022年 / 87卷 / 05期
基金：
中国国家自然科学基金;
关键词：
ELECTRON-TRANSFER; CARBON; ACTIVATION; LIGHT; PALLADIUM; CHLORIDES; STRATEGY; ANILINES; ALKENES; CASCADE;
D O I：
10.1021/acs.joc.1c02947
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An electrochemistry-promoted oxidative cleavage of (sp(3))C-C(sp(3))/H bonds in alkylarenes was developed. Various aryl alkanes can be smoothly converted into ketones/aldehydes under aerobic conditions using a user-friendly undivided cell setup. The features of air as oxidant, scalability, and mild conditions make them attractive in synthetic organic chemistry.
引用
收藏
页码：3286 / 3295
页数：10
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