Agonist trigger: what is the best approach? Agonist trigger with aggressive luteal support

被引:39
作者
Engmann, Lawrence [1 ]
Benadiva, Claudio [1 ]
机构
[1] Univ Connecticut, Ctr Hlth, Ctr Adv Reprod Serv, Dept Obstet & Gynecol,Div Reprod Endocrinol & Inf, Farmington, CT 06030 USA
关键词
GnRHa trigger; dual GnRHa trigger; OHSS; luteal phase support; low dose hCG supplementation; OVARIAN HYPERSTIMULATION SYNDROME; HUMAN CHORIONIC-GONADOTROPIN; FINAL OOCYTE MATURATION; LUTEINIZING-HORMONE SURGE; DOSE GNRH AGONIST; OVULATORY CHANGES; PRIMATE FOLLICLES; INHIBIN-A; HIGH-RISK; CYCLES;
D O I
10.1016/j.fertnstert.2011.12.020
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Although gonadotropin-releasing hormone agonist (GnRHa) trigger is effective in the prevention of ovarian hyperstimulation syndrome, lower conception rates have been reported. Intensive luteal phase support is an effective approach to improve implantation rates in women with peak E-2 levels >= 4,000 pg/mL. However, patients with peak E-2 levels <4,000 pg/mL may require a dual trigger with GnRHa and 1,000 IU hCG and intensive luteal phase support to improve implantation rates. (Fertil Steril (R) 2012;97:531-3. (C) 2012 by American Society for Reproductive Medicine.)
引用
收藏
页码:531 / 533
页数:3
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