The epidemiology and etiology of influenza-like illness in Chinese children from 2008 to 2010

被引:29
作者
Peng, Jinsong [1 ]
Kong, Wenhua [1 ,3 ]
Guo, Deyin [3 ]
Liu, Manqing [1 ]
Wang, Ying [1 ]
Zhu, Honghao [1 ]
Pang, Beibei [1 ]
Miao, Xiaoping [2 ]
Yu, Bin [1 ]
Luo, Tongyong [1 ]
Hu, Quan [1 ]
Zhou, Dunjin [1 ]
机构
[1] Wuhan Ctr Dis Prevent & Control, Wuhan 430015, Peoples R China
[2] Huazhong Univ Sci & Technol, Sch Publ Hlth, Wuhan 430074, Peoples R China
[3] Wuhan Univ, Coll Life Sci, State Key Lab Virol & Modern Virol, Res Ctr, Wuhan 430072, Peoples R China
关键词
influenza-like illness; respiratory virus; children; China; epidemiology; RESPIRATORY-TRACT INFECTIONS; HUMAN CORONAVIRUS NL63; HUMAN METAPNEUMOVIRUS; VIRAL-INFECTIONS; SYNCYTIAL-VIRUS; PCR; IDENTIFICATION; SURVEILLANCE; ADENOVIRUSES; AUSTRALIA;
D O I
10.1002/jmv.22247
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Influenza-like illness can be caused by a wide range of respiratory viruses. In order to investigate the epidemiology of viral pathogens related to influenza-like illness in children of Wuhan, the largest city in central China, throat swab samples were collected from 1,472 young patients, from July 2008 to June 2010, before and after the occurrence of the 2009 pandemic influenza A (H1N1) virus (pH1N1). It was found that 923 patients (62.7%) were positive for at least 1 virus and 90 patients (9.8%) were detected for multiple (=2) respiratory viruses by real-time PCR detection of 16 viruses. Seasonal influenza A virus was the predominant pathogen among all the 16 viruses with a positive rate of 13.3% (196/1,472), which was followed by pH1N1 (159/1,472). It was also noted that the viral distribution pattern in Wuhan changed upon the introduction of the pH1N1 virus. J. Med. Virol. 84:672678, 2012. (C) 2011 Wiley Periodicals, Inc.
引用
收藏
页码:672 / 678
页数:7
相关论文
共 43 条
[1]   Changes in the Viral Distribution Pattern after the Appearance of the Novel Influenza A H1N1 (pH1N1) Virus in Influenza-Like Illness Patients in Peru [J].
Alberto Laguna-Torres, Victor ;
Gomez, Jorge ;
Aguilar, Patricia V. ;
Ampuero, Julia S. ;
Munayco, Cesar ;
Ocana, Victor ;
Perez, Juan ;
Gamero, Maria E. ;
Carlos Arrasco, Juan ;
Paz, Irmia ;
Chavez, Edward ;
Cruz, Rollin ;
Chavez, Jaime ;
Mendocilla, Silvia ;
Gomez, Elizabeth ;
Antigoni, Juana ;
Gonzalez, Sofia ;
Tejada, Cesar ;
Chowell, Gerardo ;
Kochel, Tadeusz J. .
PLOS ONE, 2010, 5 (07) :1-8
[2]   Cloning of a human parvovirus by molecular screening of respiratory tract samples [J].
Allander, T ;
Tammi, MT ;
Eriksson, M ;
Bjerkner, A ;
Tiveljung-Lindell, A ;
Andersson, B .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (36) :12891-12896
[3]  
ANDERSON R M, 1991
[4]  
Anestad G, 2009, EURO SURVEILL, V14
[5]  
[Anonymous], EURO SURVEILL
[6]   Acute respiratory infection and influenza-like illness viral etiologies in Brazilian adults [J].
Bellei, Nancy ;
Carraro, Emerson ;
Perosa, Ana ;
Watanabe, Aripuana ;
Arruda, Eurico ;
Granato, Celso .
JOURNAL OF MEDICAL VIROLOGY, 2008, 80 (10) :1824-1827
[7]   Current status of live attenuated influenza virus vaccine in the US [J].
Belshe, RB .
VIRUS RESEARCH, 2004, 103 (1-2) :177-185
[8]   Respiratory viral infections detected by multiplex PCR among pediatric patients with lower respiratory tract infections seen at an urban hospital in Delhi from 2005 to 2007 [J].
Bharaj, Preeti ;
Sullender, Wayne M. ;
Kabra, Sushil K. ;
Mani, Kalaivani ;
Cherian, John ;
Tyagi, Vikas ;
Chahar, Harendra S. ;
Kaushik, Samander ;
Dar, Lalit ;
Broor, Shobha .
VIROLOGY JOURNAL, 2009, 6
[9]   Rhinoviruses delayed the circulation of the pandemic influenza A (H1N1) 2009 virus in France [J].
Casalegno, J. S. ;
Ottmann, M. ;
Duchamp, M. Bouscambert ;
Escuret, V. ;
Billaud, G. ;
Frobert, E. ;
Morfin, F. ;
Lina, B. .
CLINICAL MICROBIOLOGY AND INFECTION, 2010, 16 (04) :326-329
[10]  
Casalegno JS, 2009, EURO SURVEILL, V14