Label-free 3D optical imaging of microcirculation within sentinel lymph node in vivo

被引：0

作者：

Jung, Yeongri ^{[1
]}

Zhi, Zhongwei ^{[1
]}

Wang, Ruikang K. ^{[1
]}

机构：

[1] Univ Washington, Dept Bioengn, Seattle, WA 98195 USA

来源：

OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XV | 2011年 / 7889卷

关键词：

Sentinel lymph node; optical coherence tomography; sensitive optical microangiography;

D O I：

10.1117/12.875682

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Sentinel lymph node (SLN) is the first lymph node to drain wastes originated from cancerous tissue. There is a need for an in vivo imaging method that can image the intact SLN in order to further our understanding of its normal as well as abnormal functions. We report the use of ultrahigh sensitive optical microangiography (UHS-OMAG) to image functional microvascular and lymphatic vessel networks that innervate the intact lymph node in mice in vivo. The promising results show a potential role of UHS-OMAG in the future understanding and diagnosis of the SLN involvement in cancer development.

引用

页数：4

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