Subjective and objective quality of life at first presentation with psychosis

被引:10
作者
Renwick, Laoise [1 ,3 ,4 ]
Drennan, Jonathan [2 ,4 ]
Sheridan, Ann [4 ]
Owens, Liz [3 ]
Lyne, John [3 ]
O'Donoghue, Brian [6 ]
Kinsella, Anthony [3 ]
Turner, Niall [3 ]
O'Callaghan, Eadbhard
Clarke, Mary [3 ,5 ]
机构
[1] Univ Manchester, Sch Nursing Midwifery & Social Work, Room 6-304,Jean MacFarlane Bldg,Oxford Rd, Manchester M13 9PL, Lancs, England
[2] Univ Southampton, Ctr Innovat & Leadership Hlth Sci, Southampton, Hants, England
[3] Univ Coll Dublin, DETECT Early Psychosis Serv, Dublin, Ireland
[4] Univ Coll Dublin, Sch Nursing Midwifery & Hlth Syst, Dublin, Ireland
[5] Univ Coll Dublin, Sch Med, Dublin, Ireland
[6] Orygen, EPPIC, Natl Ctr Excellence Youth Mental Hlth, Melbourne, Vic, Australia
关键词
activities of daily living; psychopathology; psychotic disorder; quality of life; satisfaction; FOLLOW-UP; 1ST-EPISODE SCHIZOPHRENIA; UNTREATED PSYCHOSIS; EARLY INTERVENTION; EPISODE; DETERMINANTS; DEPRESSION; DISORDERS; SYMPTOMS; IMPACT;
D O I
10.1111/eip.12255
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Aim: Quality of life (QOL) in first-episode psychosis (FEP) is impaired when compared to non-clinical controls and several clinical factors including symptoms and untreated psychosis have been linked with poorer QOL. Measurement methods are varied, however, resulting in inconsistent findings and there is a need to simultaneously combine subjective and objective measures of QOL. Methods: We examined both subjective (n = 128) and objective QOL (n = 178) in a catchment area cohort of individuals with FEP (n = 222) to determine correspondence between patient satisfaction and clinician-rated functional domains. We also examined the contribution of socio-demographic and clinical characteristics to both subjective and objective QOL. Results: There were complex relationships between subjective and objective QOL domains in that patient's assessments of health status (psychological well-being, symptoms/outlook, physical health) were not correlated with clinicians but there were strong correlations between social functioning domains (occupation, social relations, financial status and activities of daily living) assessed by patients and clinicians. Longer duration of untreated psychosis, being treated as an inpatient, higher positive symptoms and poorer social functioning in client-rated QOL domains predicted poorer objective QOL. Conclusion: We found that both subjective and objective assessments of QOL displayed a degree of clinical utility demonstrated by relationships between clinical factors and both QOL perspectives. Moreover, the lack of association between patient characteristics and QOL shows some potential malleability of QOL outcomes through intervention as there were several clinical factors linked with both subjective and objective QOL.
引用
收藏
页码:401 / 410
页数:10
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