Copper-Catalyzed Oxytrifluoromethylation of Unactivated Aikenes

被引：351
作者：
Zhu, Rong [1 ]
Buchwald, Stephen L. [1 ]
机构：
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 134卷 / 30期
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
HYPERVALENT IODINE; ELECTROPHILIC TRIFLUOROMETHYLATION; RUTHENIUM(II) COMPLEX; TERMINAL ALKENES; ARYL FLUORIDES; BOND FORMATION; PERFLUOROALKYLATION; FUNCTIONALIZATION; CONVERSION; CHLORIDES;
D O I：
10.1021/ja305840g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A mild, versatile, and convenient method for the efficient oxytrifluoromethylation of unactivated alkenes based on a copper-catalyzed coddative difunctionalization strategy has been developed. This methodology provides access to a variety of classes of synthetically useful CF3-containing building blocks from simple starting materials.
引用
收藏
页码：12462 / 12465
页数：4
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