Does intranasal steroid spray technique affect side effects and compliance? Results of a patient survey

被引:37
作者
Ganesh, V. [1 ]
Banigo, A. [2 ]
McMurran, A. E. L. [2 ]
Shakeel, M. [2 ]
Ram, B. [2 ]
机构
[1] Univ Aberdeen, Sch Med & Dent, Aberdeen, Scotland
[2] Aberdeen Royal Infirm, Dept Otolaryngol, Foresterhill, Aberdeen AB25 2ZN, Scotland
关键词
Nasal Sprays; Nasal Aerosol; Adverse Effects; Epistaxis; Patient Compliance; INHALER TECHNIQUE; NASAL SPRAY; ADHERENCE; RHINITIS;
D O I
10.1017/S0022215117002080
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background: Intranasal steroid sprays are fundamental in the medical management of inflammatory rhinological conditions. Side effects are common, but these may be related to the method of application rather than the medication itself. Methods: A survey was distributed to patients using intranasal steroid sprays at the ENT out-patient clinic at Aberdeen Royal Infirmary over three months. This evaluated the spray technique used, side effects and compliance. Results: Of 103 patients, 22 patients (21.4 per cent) reported side effects, including nasal irritation and epistaxis. Of the 20 patients with epistaxis, 80 per cent used an ipsilateral hand technique (p = 0.01). Thirty patients demonstrated poor compliance because of lack of symptom improvement or side effects. Seventy-seven per cent of this group used the ipsilateral hand technique. Conclusion: Patients who used their ipsilateral hand to apply the intranasal steroid spray were more likely to develop epistaxis and have poor compliance than those who used other techniques. Patients who struggle with compliance because of side effects should avoid this method of intranasal steroid application.
引用
收藏
页码:991 / 996
页数:6
相关论文
共 15 条
[1]   The assessment of topical nasal drug distribution [J].
Aggarwal, R ;
Cardozo, A ;
Homer, JJ .
CLINICAL OTOLARYNGOLOGY, 2004, 29 (03) :201-205
[2]   Topical nasal steroids for intermittent and persistent allergic rhinitis in children [J].
Al Sayyad, J. J. ;
Fedorowicz, Z. ;
Alhashimi, D. ;
Jamal, A. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2007, (01)
[3]   A study of intranasal distribution of azelastine hydrochloride aqueous nasal spray with different spray techniques [J].
Bateman, ND ;
Whymark, AD ;
Clifton, NJ ;
Woolford, TJ .
CLINICAL OTOLARYNGOLOGY, 2002, 27 (05) :327-330
[4]   Epistaxis and its relationship to handedness with use of intranasal steroid spray [J].
Benninger, Michael S. .
ENT-EAR NOSE & THROAT JOURNAL, 2008, 87 (08) :463-465
[5]   Techniques of intranasal steroid use [J].
Benninger, MS ;
Hadley, JA ;
Osguthorpe, JD ;
Marple, BF ;
Leopold, DA ;
Derebery, MJ ;
Hannley, M .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2004, 130 (01) :5-24
[6]   Metered-Dose Inhaler Technique: The Effect of Two Educational Interventions Delivered in Community Pharmacy Over Time [J].
Bosnic-Anticevich, Sinthia Z. ;
Sinha, Harun ;
So, Stephen ;
Reddel, Helen K. .
JOURNAL OF ASTHMA, 2010, 47 (03) :251-256
[7]   Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen) [J].
Bousquet, J. ;
Khaltaev, N. ;
Cruz, A. A. ;
Denburg, J. ;
Fokkens, W. J. ;
Togias, A. ;
Zuberbier, T. ;
Baena-Cagnani, C. E. ;
Canonica, G. W. ;
van Weel, C. ;
Agache, I. ;
Ait-Khaled, N. ;
Bachert, C. ;
Blaiss, M. S. ;
Bonini, S. ;
Boulet, L. -P. ;
Bousquet, P. -J. ;
Camargos, P. ;
Carlsen, K. -H. ;
Chen, Y. ;
Custovic, A. ;
Dahl, R. ;
Demoly, P. ;
Douagui, H. ;
Durham, S. R. ;
van Wijk, R. Gerth ;
Kalayci, O. ;
Kaliner, M. A. ;
Kim, Y. -Y. ;
Kowalski, M. L. ;
Kuna, P. ;
Le, L. T. T. ;
Lemiere, C. ;
Li, J. ;
Lockey, R. F. ;
Mavale-Manuel, S. ;
Meltzer, E. O. ;
Mohammad, Y. ;
Mullol, J. ;
Naclerio, R. ;
Hehir, R. E. O. ;
Ohta, K. ;
Ouedraogo, S. ;
Palkonen, S. ;
Papadopoulos, N. ;
Passalacqua, G. ;
Pawankar, R. ;
Popov, T. A. ;
Rabe, K. F. ;
Rosado-Pinto, J. .
ALLERGY, 2008, 63 :8-+
[8]   Evaluation of inhaler technique, adherence to therapy and their effect on disease control among children with asthma using metered dose or dry powder inhalers [J].
Capanoglu, Murat ;
Misirlioglu, Emine Dibek ;
Toyran, Muge ;
Civelek, Ersoy ;
Kocabas, Can Naci .
JOURNAL OF ASTHMA, 2015, 52 (08) :838-845
[9]   Intranasal steroids versus placebo or no intervention for chronic rhinosinusitis [J].
Chong, Lee Yee ;
Head, Karen ;
Hopkins, Claire ;
Philpott, Carl ;
Schilder, Anne G. M. ;
Burton, Martin J. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2016, (04)
[10]   Different types of intranasal steroids for chronic rhinosinusitis [J].
Chong, Lee Yee ;
Head, Karen ;
Hopkins, Claire ;
Philpott, Carl ;
Burton, Martin J. ;
Schilder, Anne G. M. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2016, (04)