Reaction of 3-hydroxy-1,2,3,4-tetrahydroquinoline-2,4-diones with ethyl(triphenylphosphoranylidene) acetate

被引：18
|
作者：
Kafka, S [1 ]
Kovar, M [1 ]
Klasek, A [1 ]
Kappe, T [1 ]
机构：
[1] KARL FRANZENS UNIV GRAZ,INST ORGAN CHEM,A-8010 GRAZ,AUSTRIA
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 1996年 / 33卷 / 06期
关键词：
D O I：
10.1002/jhet.5570330667
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The Wittig reaction of 3-hydroxy-1,2,3,4-tetrahydroquinoline-2,4-diones 2 with ethyl (triphenylphosphoranylidene)acetate 3 proceeds stereoselectively to give E-4-carbethoxymethylene-1,2,3,4-tetrahydro-2-quinolones 4, which were hydrolyzed to corresponding acids 6. Butenolides 5 were detected end, in some cases, isolated as a minor product of the Wittig reaction.
引用
收藏
页码：1977 / 1982
页数：6
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