Diagnostic and Therapeutic Considerations Towards Dientamoeba fragilis in Children: A Survey Amongst General Practitioners and Pediatricians in the Netherlands

被引：1
作者：
van Kalleveen, Michael W. [1 ,2 ]
van Bergen, Merel [3 ]
Benninga, Marc A. [3 ]
Savelkoul, Paul H. M. [4 ,5 ]
Plotz, Frans B. [1 ,6 ]
de Meij, Tim G. J. [3 ]
机构：
[1] Tergooi Hosp, Dept Pediat, Blaricum, Netherlands
[2] Leiden Univ, Dept Gastroenterol & Hepatol, Med Ctr, Albinusdreef 2, NL-2333 ZA Leiden, Netherlands
[3] Amsterdam UMC, Dept Pediat Gastroenterol, Emma Childrens Hosp, Amsterdam, Netherlands
[4] Maastricht Univ, NUTRIM Sch Nutr & Translat Res Metab, Dept Med Microbiol, Med Ctr, Maastricht, Netherlands
[5] Amsterdam UMC, Locat VUmc, Dept Med Microbiol & Infect Control, Amsterdam, Netherlands
[6] Univ Amsterdam, Emmas Childrens Hosp, Dept Pediat, Amsterdam UMC, Amsterdam, Netherlands
来源：
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION | 2021年 / 73卷 / 06期
关键词：
children; diagnostics; Dientamoeba fragilis; management; therapy;
D O I：
10.1097/MPG.0000000000003297
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
This survey was undertaken to obtain insight in the attitude of Dutch physicians towards pathogenicity, diagnostic- and therapeutic approach towards Dientamoeba fragilis in children. Physicians were invited by e-mail for a questionnaire. A total of 211 of 450 physicians (46.9%) completed the questionnaire, including 67 general practitioners (GPs) and 144 pediatricians. Of all respondents, 175 of 211 (82.9%) considered D fragilis a "potential pathogen", when other causes of gastro-intestinal complaints are ruled out. Only 16 of 211 (7.6%) performed diagnostic tests regularly. Diagnostic tests were performed by 162 of 211 (77%) of respondents in children with diarrhea and abdominal pain in consideration of duration of symptoms. Fecal polymerase chain reaction (PCR) was diagnostic modality of preference. Eighty-nine of 142 (62.7%) prescribed metronidazole as antibiotic of first choice. This study shows heterogeneity in clinical practice amongst Dutch physicians regarding diagnostic- and therapeutic approach of D fragilis in children. Different attitude towards pathogenicity and inconsistent guidelines could be causative factors.
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收藏
页码：E121 / E125
页数：5
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