Post-streptococcal acute glomerulonephritis in children: clinical features and pathogenesis

被引：95

作者：

Eison, T. Matthew ^{[1
,2
]}

Ault, Bettina H. ^{[1
,2
]}

Jones, Deborah P. ^{[1
,2
]}

Chesney, Russell W. ^{[1
,2
]}

Wyatt, Robert J. ^{[1
,2
]}

机构：

[1] Univ Tennessee, Hlth Sci Ctr, Div Pediat Nephrol, Dept Pediat, Memphis, TN 38163 USA

[2] Lebonheur Childrens Hosp & Med Ctr, Childrens Fdn Res Ctr, Memphis, TN 38163 USA

来源：

PEDIATRIC NEPHROLOGY | 2011年 / 26卷 / 02期

关键词：

Acute glomerulonephritis; Group A beta-hemolytic streptococcus; Nephritogenic; POST-STREPTOCOCCAL GLOMERULONEPHRITIS; GROUP-A STREPTOCOCCI; CIRCULATING IMMUNE-COMPLEXES; ACUTE RHEUMATIC-FEVER; RENAL BIOPSY SPECIMENS; TERMINAL COMPLEMENT COMPLEXES; HENOCH-SCHONLEIN PURPURA; NEPHRITOGENIC STREPTOCOCCI; NATURAL-HISTORY; ACUTE NEPHRITIS;

D O I：

10.1007/s00467-010-1554-6

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Post-streptococcal acute glomerulonephritis (PSAGN) is one of the most important and intriguing conditions in the discipline of pediatric nephrology. Although the eventual outcome is excellent in most cases, PSAGN remains an important cause of acute renal failure and hospitalization for children in both developed and underdeveloped areas. The purpose of this review is to describe both the typical and less common clinical features of PSAGN, to outline the changes in the epidemiology of PSAGN over the past 50 years, and to explore studies on the pathogenesis of the condition with an emphasis on the search for the elusive nephritogenic antigen.

引用

页码：165 / 180

页数：16

共 192 条

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