Experimental and Theoretical Studies on a Simple S-S-Bridged Dimeric Schiff Base: Selective Chromo-Fluorogenic Chemosensor for Nanomolar Detection of Fe2+ & Al3+ Ions and Its Varied Applications

被引:72
作者
David, Charles Immanuel [2 ]
Bhuvanesh, Nanjan [2 ]
Jayaraj, Haritha [2 ]
Thamilselvan, Annadurai [3 ]
Devi, Duraisamy Parimala [1 ]
Abiram, Angamuthu [1 ]
Prabhu, Jeyaraj [2 ]
Nandhakumar, Raju [2 ]
机构
[1] Karunya Inst Technol & Sci Deemed Be Univ, Dept Phys, Coimbatore 641114, Tamil Nadu, India
[2] Karunya Inst Technol & Sci Deemed Be Univ, Dept Chem, Coimbatore 641114, Tamil Nadu, India
[3] CSIR, Electro Organ Div, Cent Electrochem Res Inst, CECRI, Karaikkudi 630003, Tamil Nadu, India
关键词
FLUORESCENCE TURN-ON; MOLECULAR-STRUCTURE; LIVING CELLS; COLORIMETRIC SENSOR; ALZHEIMERS-DISEASE; REVERSIBLE SENSOR; IRON-METABOLISM; AQUEOUS-MEDIA; ALUMINUM IONS; LUMO ANALYSIS;
D O I
10.1021/acsomega.9b04294
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A simple S-S (disulfide)-bridged dimeric Schiff base probe, L, has been designed, synthesized, and successfully characterized for the specific recognition of Al3+ and Fe2+ ions as fluorometric and colorimetric "turn-on" responses in a dimethylformamide (DMF)-H2O solvent mixture, respectively. The probe L and each metal ion bind through a 1:1 complex stoichiometry, and the plausible sensing mechanism is proposed based on the inhibition of the photoinduced electron transfer process (PET). The reversible chemosensor L showed high sensitivity toward Al3+ and Fe2+ ions, which was analyzed by fluorescence and UV-vis spectroscopy techniques up to nanomolar detection limits, 38.26 X 10(-9) and 17.54 x 10(-9) M, respectively. These experimental details were advocated by density functional theory (DFT) calculations. The practical utility of the chemosensor L was further demonstrated in electrochemical sensing, in vitro antimicrobial activity, molecular logic gate function, and quantification of the trace amount of Al3+ and Fe2+ ions in real water samples.
引用
收藏
页码:3055 / 3072
页数:18
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