Severe thrombocytopenia and microangiopathic hemolytic anemia in pregnancy: A guide for the consulting hematologist

被引：19
作者：
Perez Botero, Juliana [1 ,2 ]
Reese, Jessica A. [3 ]
George, James N. [3 ,4 ]
McIntosh, Jennifer J. [5 ]
机构：
[1] Med Coll Wisconsin, Dept Med, Div Hematol & Oncol, 618 18 St, Milwaukee, WI 53233 USA
[2] Versiti, Blood Ctr Wisconsin, Milwaukee, WI USA
[3] Univ Oklahoma, Hudson Coll Publ Hlth, Dept Biostat & Epidemiol, Oklahoma City, OK USA
[4] Univ Oklahoma, Hlth Sci Ctr, Dept Med, Hematol Oncol Sect, Oklahoma City, OK USA
[5] Med Coll Wisconsin, Dept Obstet & Gynecol, Div Maternal Fetal Med, Milwaukee, WI 53226 USA
来源：
AMERICAN JOURNAL OF HEMATOLOGY | 2021年 / 96卷 / 12期
关键词：
INDUCED THROMBOTIC MICROANGIOPATHY; REDUCED ADAMTS13 ACTIVITY; UPSHAW-SCHULMAN SYNDROME; OUTCOMES; PURPURA; MANAGEMENT; DIAGNOSIS; THERAPY; GENE; DIVERSITY;
D O I：
10.1002/ajh.26328
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A hematologist receives a call from a maternal-fetal medicine (MFM) physician about a previously healthy patient who became ill at 25 weeks' gestation. Her mental status is deteriorating. There are signs of fetal distress. Platelet count and hemoglobin are falling. The MFM physician is considering the hemolysis, elevated liver enzymes and low platelet count (HELLP) syndrome. For the hematologist, everything seems unfamiliar. Our goal is to provide hematologists with the fundamental knowledge required for understanding and managing these patients who become suddenly and seriously ill during pregnancy and in whom thrombocytopenia and microangiopathic hemolytic anemia are part of their presentation.
引用
收藏
页码：1655 / 1665
页数：11
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