Synergistic Cancer Therapeutic Effects of Locally Delivered Drug and Heat Using Multifunctional Nanoparticles

被引:154
作者
Lee, Sun-Mi [1 ]
Park, Huiyul [1 ]
Yoo, Kyung-Hwa [1 ,2 ]
机构
[1] Yonsei Univ, Natl Core Res Ctr Nanomed Technol, Seoul 120749, South Korea
[2] Yonsei Univ, Dept Phys, Seoul 120749, South Korea
关键词
GOLD NANOCAGES; HYPERTHERMIA; ENHANCEMENT; DESTRUCTION; ADRIAMYCIN; AGENTS; TUMORS;
D O I
10.1002/adma.201001040
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Doxorubicin-loaded PEG-PLGA-Au half-shell nanoparticles provide multifunctions, such as photothermal treatment, photothermally controlled drug delilvery, and in vivo optical imaging. In addition, the combined doxorubicin and photothermal treatments using these multifunctional nanoparticles show synergistic therapeutic effects.
引用
收藏
页码:4049 / 4053
页数:5
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