Toxicity studies of Rhizoma Polygonati Odorati

被引：15

作者：

Chen, HB

Feng, RZ

Guo, Y

Sun, LH

Zhou, YP

Jiang, JL

机构：

[1] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100094, Peoples R China

[2] Minist Hlth, Inst Drug Control & Biol Prod, Dept Pharmacol & Toxicol, Beijing 100050, Peoples R China

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2001年 / 74卷 / 03期

关键词：

Rhizoma Polygonati Odorati; acute toxicity; chronic toxicity; Ames test; bone marrow micronucleus test; sperm malformation test;

D O I：

10.1016/S0378-8741(00)00358-5

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The toxicity of the water-soluble extract of Rhizoma Polygonati Odorati was studied in the present investigation, which included its acute toxicity, chronic toxicity, and genetic toxicity. The aqueous extract of Rhizoma Polygonati Odorati did not cause seriously abnormal signs or death to animals in the acute toxicity test and in the 6-month chronic toxicity test. Neither was genetic toxicity found in the Ames test, the micronucleus test of bone marrow and the sperm malformation test in mice. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：221 / 224

页数：4