Lymphatic malformations: Review of current treatment

被引:153
作者
Perkins, Jonathan A. [1 ,2 ]
Manning, Scott C. [1 ,2 ]
Tempero, Richard M. [3 ]
Cunningham, Michael J. [4 ,5 ]
Edmonds, Joseph L., Jr. [6 ,9 ,10 ,11 ,12 ]
Hoffer, Fredric A. [7 ]
Egbert, Mark A. [8 ]
机构
[1] Seattle Childrens Hosp, Div Pediat Otolaryngol Head & Neck Surg, Seattle, WA 98105 USA
[2] Univ Washington, Dept Otolaryngol Head & Neck Surg, Seattle, WA 98195 USA
[3] Boys Town Natl Res Hosp, Omaha, NE 68131 USA
[4] Harvard Univ, Massachusetts Eye & Ear Infirm, Sch Med, Dept Otolaryngol, Boston, MA USA
[5] Harvard Univ, Sch Med, Dept Otol & Laryngol, Boston, MA 02115 USA
[6] Childrens ENT Houston, Houston, TX USA
[7] Univ Washington, Dept Radiol, Seattle Childrens Hosp, Seattle, WA 98195 USA
[8] Univ Washington, Dept Oral & Maxillofacial Surg, Seattle Childrens Hosp, Seattle, WA 98195 USA
[9] Baylor Coll Med, Dept Otolaryngol, Houston, TX 77030 USA
[10] Baylor Coll Med, Div Plast Surg, Houston, TX 77030 USA
[11] Weill Cornell Coll Med, Dept Otolaryngol, New York, NY USA
[12] Univ Texas Houston, Sch Med, Dept Otolaryngol, Houston, TX USA
关键词
CYSTIC HYGROMA; PERCUTANEOUS SCLEROTHERAPY; OK-432; LYMPHANGIOMA; INJECTION; CHILDREN; MANAGEMENT; THERAPY; NECK; HEAD;
D O I
10.1016/j.otohns.2010.02.026
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
OBJECTIVE: Summarize current knowledge of lymphatic malformation medical, sclerotherapy, and surgical treatment; and highlight areas of treatment controversy and treatment difficulty that need improvement. METHODS: Panel presentation of various aspects of lymphatic malformation treatment. RESULTS: The mainstay of lymphatic malformation treatment has been surgical resection, which has been refined through lesion staging and radiographic characterization. Intralesional sclerotherapy in macrocystic lymphatic malformations is effective. Suprahyoid microcystic lymphatic malformations are more difficult to treat than macrocystic lymphatic malformations in the infrahyoid and posterior cervical regions. Bilateral suprahyoid lymphatic malformations require staged treatment to prevent complications, Lymphatic malformation treatment planning is primarily determined by the presence or possibility of functional compromise. Problematic areas include chronic lymphatic malformation inflammation, dental health maintenance, macroglossia, airway obstruction, and dental malocclusion. CONCLUSIONS: Lymphatic malformation treatment improvements have been made through radiographic characterization and staging of lymphatic malformations. Direct malformation involvement of the upper aerodigestive tract can cause significant functional compromise that is difficult to treat. (C) 2010 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.
引用
收藏
页码:795 / 803
页数:9
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