Deuterium exchange as an indicator of hydrogen bond donors and acceptors

被引:42
|
作者
Steffel, Lauren R. [1 ]
Cashman, Timothy J. [1 ]
Reutershan, Michael H. [1 ]
Linton, Brian R. [1 ]
机构
[1] Bowdoin Coll, Dept Chem, Brunswick, ME 04011 USA
关键词
D O I
10.1021/ja076185s
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Hydrogen-deuterium exchange has been used to determine the hydrogen bonding preferences of a select group of small peptides in organic solvents. This kinetic analysis permitted comparison of hydrogen bond strengths in relation to controls and also indicated the identity of both hydrogen bond donors and hydrogen bond acceptors.
引用
收藏
页码:12956 / +
页数:3
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