Assessing dimerisation degree and cooperativity in a biomimetic small-molecule model by pulsed EPR

被引：21

作者：

Ackermann, K.

Giannoulis, A.

Cordes, D. B.

Slawin, A. M. Z.

Bode, B. E. ^{[1
]}

机构：

[1] Univ St Andrews, EaStCHEM Sch Chem, Biomed Sci Res Complex, St Andrews KY16 9ST, Fife, Scotland

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 25期

基金：

英国工程与自然科学研究理事会;

关键词：

ELECTRON DOUBLE-RESONANCE; DISTANCE MEASUREMENTS; SPIN ECHO; TERPYRIDINE; PROTEINS; ELDOR; DEER;

D O I：

10.1039/c4cc08656b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pulsed electron paramagnetic resonance (EPR) spectroscopy is gaining increasing importance as a complementary biophysical technique in structural biology. Here, we describe the synthesis, optimisation, and EPR titration studies of a spin-labelled terpyridine Zn(II) complex serving as a small-molecule model system for tuneable dimerisation.

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页码：5257 / 5260

页数：4

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