Novel approaches to the treatment of intracerebral haemorrhage

被引：23

作者：

Staykov, Dimitre ^{[2
]}

Huttner, Hagen B. ^{[2
]}

Koehrmann, Martin ^{[2
]}

Bardutzky, Juergen ^{[2
]}

Schellinger, Peter D. ^{[1
,2
]}

机构：

[1] Johannes Wesling Hosp, Dept Neurol, D-32429 Minden, Germany

[2] Univ Clin Erlangen, Dept Neurol, D-91054 Erlangen, Germany

来源：

INTERNATIONAL JOURNAL OF STROKE | 2010年 / 5卷 / 06期

关键词：

cerebral oedema; haematoma evacuation; hypothermia; intracerebral haemorrhage; intraventricular fibrinolysis; intraventricular haemorrhage; lumbar drainage; treatment; CEREBRAL-BLOOD-FLOW; EXTERNAL VENTRICULAR DRAINAGE; BRAIN-BARRIER PERMEABILITY; ACTIVATED FACTOR-VII; INTRAVENTRICULAR HEMORRHAGE; EDEMA DEVELOPMENT; RAT MODEL; MATRIX METALLOPROTEINASES; CONSERVATIVE TREATMENT; PERIHEMORRHAGIC ZONE;

D O I：

10.1111/j.1747-4949.2010.00487.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Intracerebral haemorrhage is the most devastating subtype of stroke. It affects approximately two million patients worldwide every year and is a major cause of morbidity and mortality. After decades of research, we still face the fact that there is no evidence-based treatment strategy for this disease. However, research has contributed to a better understanding of the pathophysiology of intracerebral haemorrhage and also to the identification of new treatment targets. Several novel aspects of treatment of spontaneous intracerebral haemorrhage are reviewed in the present article.

引用

页码：457 / 465

页数：9

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