Preeclampsia and future maternal health

被引：110

作者：

Carty, David M. ^{[1
]}

Delles, Christian ^{[1
]}

Dominiczak, Anna F. ^{[1
]}

机构：

[1] Univ Glasgow, Fac Med, BHF Glasgow Cardiovasc Res Ctr, Glasgow G12 8TA, Lanark, Scotland

来源：

JOURNAL OF HYPERTENSION | 2010年 / 28卷 / 07期

关键词：

cardiovascular disease; hypertension; preeclampsia; PULSE-WAVE ANALYSIS; C-REACTIVE PROTEIN; GENOME-WIDE SCAN; HYPERTENSIVE DISORDERS; CARDIOVASCULAR-DISEASE; SUSCEPTIBILITY LOCUS; INSULIN-RESISTANCE; NORMAL-PREGNANCY; BLOOD-PRESSURE; SHORT-TERM;

D O I：

10.1097/HJH.0b013e32833a39d0

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Preeclampsia is a multisystem disorder that complicates 3-8% of pregnancies in the Western world, and is a major source of morbidity and mortality worldwide. Although it is a disease unique to pregnancy, evidence has mounted in recent years that preeclampsia has important implications for future maternal health, in particular cardiovascular health. In this review we examine epidemiological evidence for this relationship, and examine potential mechanisms such as insulin resistance, genetic factors and endothelial dysfunction that may explain the relationship. In addition we explore potential future avenues of research into the field, such as genomics, proteomics and metabolomics. J Hypertens 28: 1349-1355 (C) 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins.

引用

页码：1349 / 1355

页数：7

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