Management of chikungunya arthritis

被引:21
作者
Kennedy Amaral Pereira, J. [1 ]
Schoen, Robert T. [2 ]
机构
[1] Fac Med Estacio Juazeiro do Norte, Juazeiro Do Norte, Ceara, Brazil
[2] Yale Univ, Sch Med, Rheumatol Sect, New Haven, CT 06520 USA
关键词
Chikungunya virus; Chronic arthritis post-Chikungunnya; Chikungunya fever arthritis; Methotrexate; US VIRGIN-ISLANDS; MUSCULOSKELETAL PAIN; VIRUS-INFECTION; MANIFESTATIONS; ARTHRALGIA; DISEASE; METHOTREXATE; OUTBREAK; FEVER;
D O I
10.1007/s10067-017-3766-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chikungunya fever (CHIKF) is an emerging viral infection that has spread widely, along with its Aedes vectors, throughout the tropics and beyond, causing explosive epidemics of both acute illness and persistent disabling arthritis. There is an urgent need to mitigate the devastating impact of this illness, through vector control, personal protection, and possibly vaccine development. There is also a need to improve treatment for both acute illness and chronic arthritis. In this review, we will review the emergence of CHIK, what is known about pathogenesis and clinical manifestations, and then focus on current understanding of how to treat individual patients, in particular, those who develop chronic arthritis.
引用
收藏
页码:2179 / 2186
页数:8
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