Case report:: Schistosoma mansoni infection:: failure of standard treatment with praziquantel in a returned traveller

被引：35
作者：
Lawn, SD
Lucas, SB
Chiodini, PL
机构：
[1] Hosp Trop Dis, London, England
[2] St Thomas Hosp, Dept Histopathol, London, England
来源：
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2003年 / 97卷 / 01期
关键词：
schistosomiasis; Schistosoma mansoni; chemotherapy; praziquantel; drug resistance; traveller;
D O I：
10.1016/S0035-9203(03)90038-1
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Heavy reliance upon praziquantel for the treatment of schistosomiasis raises concerns over potential development of drug resistance. We describe a British traveller who acquired Schistosoma mansoni infection in East Africa and in whom repeated standard 40 mg/kg doses of praziquantel failed to clear the infection despite no opportunity for reinfection.
引用
收藏
页码：100 / 101
页数：2
相关论文
共 8 条
[1]   Interpreting low praziquantel cure rates of Schistosoma mansoni infections in Senegal [J].
Danso-Appiah, A ;
De Vlas, SJ .
TRENDS IN PARASITOLOGY, 2002, 18 (03) :125-129
[2]   Drug resistance in human helminths: Current situation and lessons from livestock [J].
Geerts, S ;
Gryseels, B .
CLINICAL MICROBIOLOGY REVIEWS, 2000, 13 (02) :207-+
[3]   Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance?: An overview of the evidence [J].
Gryseels, B ;
Mbaye, A ;
De Vlas, SJ ;
Stelma, FF ;
Guissé, F ;
Van Lieshout, L ;
Faye, D ;
Diop, M ;
Ly, A ;
Tchuem-Tchuenté, LA ;
Engels, D ;
Polman, K .
TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2001, 6 (11) :864-873
[4]  
Hamilton JV, 1998, PARASITOLOGY, V117, pS41
[5]   Characterization of isolates of Schistosoma mansoni from Egyptian villagers that tolerate high doses of praziquantel [J].
Ismail, M ;
Metwally, A ;
Farghaly, A ;
Bruce, J ;
Tao, LF ;
Bennett, JL .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1996, 55 (02) :214-218
[6]   Detection by polymerase chain reaction of Schistosoma mansoni DNA in human serum and feces [J].
Pontes, LA ;
Dias-Neto, E ;
Rabello, A .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2002, 66 (02) :157-162
[7]   EPIDEMIOLOGY OF SCHISTOSOMA-MANSONI INFECTION IN A RECENTLY EXPOSED COMMUNITY IN NORTHERN SENEGAL [J].
STELMA, FF ;
TALLA, I ;
POLMAN, K ;
NIANG, M ;
STURROCK, RF ;
DEELDER, AM ;
GRYSEELS, B .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1993, 49 (06) :701-706
[8]   Presentation and outcome of 1107 cases of schistosomiasis from Africa diagnosed in a non-endemic country [J].
Whitty, CJM ;
Mabey, DC ;
Armstrong, M ;
Wright, SG ;
Chiodini, PL .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2000, 94 (05) :531-534
1