The AAA Risk Factors Scale: A New Model to Screen for the Risk of Asthma, Allergic Rhinitis and Atopic Dermatitis in Children

被引:11
作者
Hallit, Souheil [1 ,2 ,3 ,4 ,5 ,6 ]
Raherison, Chantal [5 ,7 ]
Malaeb, Diana [8 ]
Hallit, Rabih [3 ]
Kheir, Nelly [9 ]
Salameh, Pascale [1 ,6 ,10 ]
机构
[1] Lebanese Univ, Fac Pharm, Beirut, Lebanon
[2] St Joseph Univ, Fac Pharm, Beirut, Lebanon
[3] Holy Spirit Univ Kaslik, Fac Med & Med Sci, Beirut, Lebanon
[4] Psychiat Hosp Cross, Res Dept, Jal Eddib, Lebanon
[5] Univ Bordeaux, Occupat Hlth Environm Res Team, BPH Bordeaux Populat Hlth Res Ctr U1219, INSERM, Bordeaux, France
[6] Lebanese Univ, INSPECT LB Inst Natl Sante Publ Epidemiol Clin &, Fac Publ Hlth, Beirut, Lebanon
[7] Univ Hosp, Dept Pneumol, Bordeaux, France
[8] Lebanese Int Univ, Sch Pharm, Beirut, Lebanon
[9] Lebanese Univ, Fac Sci, Beirut, Lebanon
[10] Lebanese Univ, Fac Med Sci, Beirut, Lebanon
关键词
Allergic disease; Eczema; Humidity; Allergic rhinitis; Asthma; Atopic dermatitis; Screening; Children; PESTICIDE EXPOSURE; CHILDHOOD; DISEASES; PREGNANCY; ALCOHOL; SMOKING;
D O I
10.1159/000490704
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To create an allergic disease risk factors scale score that would screen for the risk assessment of asthma, allergic rhinitis and atopic dermatitis (AD) in children from 3 to 17 years. Methods: This case-control study, conducted between December 2015 and April 2016, enrolled 1,274 children. The allergic disease risk factors scale was created by combining environmental, exposure to toxics during pregnancy and breastfeeding and parental history of allergic diseases. Results: Playing on carpets, male gender, child's respiratory problems or history of eczema before the age of 2 years, and humidity significantly increased the odds of allergies in the child. Maternal waterpipe smoking, maternal history of rhinitis, history of asthma in the mother or the father, along with the maternal drug intake or alcohol consumption during pregnancy significantly increased the odds of allergies in the child. There was a significant increase in allergy diseases per category of the allergic disease risk factors scale (p < 0.001 for trend). Scores 2.60 best represented control individuals, while scores > 5.31 best represented children with allergic diseases. Conclusion: Allergic diseases seem to be linked to several risk factors in our population of school children. Many environmental factors might be incriminated in these allergic diseases. (c) 2018 The Author(s) Published by S. Karger AG, Basel
引用
收藏
页码:472 / 480
页数:9
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