Rhenium(V) gluconate, a suitable precursor for the preparation of rhenium(V) complexes

被引：28

作者：

Noll, B ^{[1
]}

Kniess, T ^{[1
]}

Friebe, M ^{[1
]}

Spies, H ^{[1
]}

Johannsen, B ^{[1
]}

机构：

[1] ROSSENDORF INC,FORSCHUNGSZENTRUM ROSSENDORF EV,INST BIOANORGAN & RADIOPHARMAZEUT CHEM,D-01314 DRESDEN,GERMANY

来源：

ISOTOPES IN ENVIRONMENTAL AND HEALTH STUDIES | 1996年 / 32卷 / 01期

关键词：

polarography; radiotherapeuticals; rhenium(V) complexes; rhenium(V) gluconate;

D O I：

10.1080/10256019608036290

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Reduction of perrhenate with stannous chloride at an excess of sodium gluconate in aqueous solution results in formation of rhenium(V) gluconate. The reaction proceeds slowly compared to that of pertechnetate. Aqueous solutions of rhenium(V) gluconate can be prepared down to a concentration level of at least 10(-4) mol . l(-1) within two hours. The usefulness of rhenium(V) gluconate to serve as a precursor for preparation of oxorhenium(V) complexes as potential radiotherapeutic agents is revealed by subsequent ligand exchange reactions carried out with mercaptoacetyldiglycine, 3-thiapentane-dithiol-1,5/butanethiol and with 2-aminobenzenethiol.

引用

页码：21 / 29

页数：9

共 14 条

[1]

BREITZ HB, 1992, J NUCL MED, V33, P1099

[2] SYNTHESIS AND CHARACTERIZATION OF COMPLEXES CONTAINING THE BIS(1,2-DIOLATO)-OXOTECHNETIUM(V) CORE [J].