Data structure and related methods for pooled meta-analysis

被引:0
作者
Roeder, SW [1 ]
机构
[1] UFZ Helmholtz Ctr Environm Res, Dept Human Exposure Res & Epidemiol, D-04301 Leipzig, Germany
来源
8TH WORLD MULTI-CONFERENCE ON SYSTEMICS, CYBERNETICS AND INFORMATICS, VOL I, PROCEEDINGS: INFORMATION SYSTEMS, TECHNOLOGIES AND APPLICATIONS | 2004年
关键词
meta-analysis; pooled meta-analysis; meta-data; data description; data management;
D O I
暂无
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Some questions in statistics can only be answered with a multi period setup (e.g. longitudinal studies). A widely used approach is called meta-analysis. This paper uses the variant pooled metaanalysis and shows data structures and methods for performing such an analysis. Pooled meta-analysis requires concatenating the primary data sets. If variables have different specifications over periods, then this concatenation is difficult. Therefore a data structure for describing the variables from different periods or studies and their codes is necessary. Methods for generating data sets complete these data structures. The shown data structure is founded on a description of each real variable. This description includes original question, coding and specification, range, measurement unit, categories and dependencies between the variables. The related method analyzes the dependencies between the variables and is able to generate a data set for further analysis which holds the data from selected variables from selected periods. Constraint violations such as missing value codes or values outside specification can be recognized. The shown algorithm allows easier handling of variables in complex data structures for pooled meta-analysis.
引用
收藏
页码:211 / 215
页数:5
相关论文
共 9 条
  • [1] Blettner M, 1998, MED KLIN, V93, P442, DOI 10.1007/BF03042643
  • [2] EGGER M, 1997, BMJ-BRIT MED J, V315, P22
  • [3] FERRI F, 2003, COMPUTER METHODS PRO, V40, P43
  • [4] Friedman C, 1990, GEN RELATIONAL SCHEM
  • [5] GALL W, 2000, COMPUTER METHODS PRO, V66, P153
  • [6] Commentary: Meta-analysis of individual participants' data in genetic epidemiology
    Ioannidis, JPA
    Rosenberg, PS
    Goedert, JJ
    O'Brien, TR
    [J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 2002, 156 (03) : 204 - 210
  • [7] Organization of heterogeneous scientific data using the EAV/CR representation
    Nadkarni, PM
    Marenco, L
    Chen, R
    Skoufos, E
    Shepherd, G
    Miller, P
    [J]. JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, 1999, 6 (06) : 478 - 493
  • [8] STEWART LA, 2003, STATMED, P2057
  • [9] Interpreting epidemiological evidence: how meta-analysis and causal inference methods are related
    Weed, DL
    [J]. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2000, 29 (03) : 387 - 390