Enhanced reactivity of dinuclear Copper(I) acetylides in dipolar cycloadditions

被引：196

作者：

Ahlquist, Marten

Fokin, Valery V.

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Tech Univ Denmark, Dept Chem, DK-2800 Lyngby, Denmark

来源：

ORGANOMETALLICS | 2007年 / 26卷 / 18期

关键词：

D O I：

10.1021/om700669v

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Dinuclear alkynyl copper(I) complexes exhibit superior reactivity toward organic azides compared to their monomeric analogues. DFT studies indicate that the second copper center facilitates the formation of the cupracycle in the rate-determining step and stabilizes the metallacycle intermediate itself. These findings support the experimentally determined rate law and shed light on the origin of high reactivity of the in situ generated copper acetylides.

引用

页码：4389 / 4391

页数：3

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