Quorum sensing and its relevance to infectious diseases

被引:68
作者
Donabedian, H [1 ]
机构
[1] Med Coll Ohio, Div Infect Dis, Dept Internal Med, Toledo, OH 43614 USA
[2] Med Coll Ohio, Div Infect Dis, Dept Internal Med, Toledo, OH 43614 USA
[3] Med Coll Ohio, Div Infect Dis, Dept Microbiol, Toledo, OH 43614 USA
[4] Med Coll Ohio, Div Infect Dis, Dept Immunol, Toledo, OH 43614 USA
关键词
D O I
10.1053/jinf.2002.1120
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Quorum sensing allows bacteria to detect the density of their own species and alter their metabolism to take advantage of this density. Quorum sensing is used by a wide variety of bacteria including human pathogens. Quorum sensing genes are important for the pathogenic potential of Pseudomonas aeruginosa and Staphylococcus aureus, as well as other invasive bacteria. An understanding of quorum sensing may lead to new therapeutic strategies. (C) 2003 The British Infection Society. Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:207 / 214
页数:8
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