American Academy of Dermatology Guidelines: Awareness of comorbidities associated with atopic dermatitis in adults

被引：99

作者：

Davis, Dawn M. R. ^{[1
]}

Drucker, Aaron M. ^{[2
,3
]}

Alikhan, Ali ^{[4
]}

Bercovitch, Lionel ^{[5
]}

Cohen, David E. ^{[6
]}

Darr, Jennifer M. ^{[7
]}

Eichenfield, Lawrence F. ^{[8
,9
]}

Frazer-Green, Lindsy ^{[10
]}

Paller, Amy S. ^{[11
,12
]}

Silverberg, Jonathan, I ^{[13
]}

Singh, Anne Marie ^{[14
]}

Sidbury, Robert ^{[15
,16
]}

机构：

[1] Mayo Clin, Dept Dermatol, Rochester, MN USA

[2] Univ Toronto, Dept Med, Div Dermatol, Toronto, ON, Canada

[3] Womens Coll Hosp, Womens Coll, Res Inst, Toronto, ON, Canada

[4] Sutter Med Fdn, Dept Dermatol, Sacramento, CA USA

[5] Brown Univ, Dept Dermatol, Warren Alpert Med Sch, Providence, RI 02912 USA

[6] NYU, Ronald O Perelman Dept Dermatol, New York, NY USA

[7] Natl Jewish Hlth, Dept Pediat, Denver, CO USA

[8] Univ Calif San Diego, San Diego, CA 92103 USA

[9] Rady Childrens Hosp, Div Pediat & Adolescent Dermatol, San Diego, CA USA

[10] Amer Acad Dermatol, 9500 Bryn Mawr Ave,Suite 500, Rosemont, IL 60018 USA

[11] Northwestern Univ, Dept Dermatol, Feinberg Sch Med, Chicago, IL 60611 USA

[12] Northwestern Univ, Dept Pediat, Feinberg Sch Med, Chicago, IL 60611 USA

[13] George Washington Univ, Dept Dermatol, Sch Med & Hlth Sci, Washington, DC USA

[14] Univ Wisconsin, Dept Pediat, Sch Med & Publ Hlth, Madison, WI USA

[15] Univ Washington, Div Dermatol, Dept Pediat, Sch Med, Seattle, WA 98195 USA

[16] Seattle Childrens Hosp, Seattle, WA USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2022年 / 86卷 / 06期

关键词：

alcohol; allergies; atopic dermatitis; cardiovascular disease; comorbidities; dermatology; diabetes; guidelines; mental health; metabolic syndrome; obesity; osteoporosis; skin infection; CARDIOVASCULAR RISK-FACTORS; 2013; NATIONAL-HEALTH; QUALITY-OF-LIFE; ALLERGIC RHINITIS; MYOCARDIAL-INFARCTION; SUICIDAL IDEATION; ALOPECIA-AREATA; SYSTEMIC INFECTIONS; ISCHEMIC-STROKE; CO-MORBIDITY;

D O I：

10.1016/j.jaad.2022.01.009

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background: Studies found associations between atopic dermatitis (AD) and various comorbidities. Objective: To appraise evidence of the association between AD and comorbidities among adults. Methods: Our multidisciplinary work group conducted a systematic review of the association between AD and selected comorbidities. We applied the Grading of Recommendations, Assessment, Development, and Evaluation for prognosis approach for assessing the certainty of the evidence, providing statements of association based on the available evidence. Results: Analysis of the evidence resulted in 32 statements. Clear evidence of the association of AD in adults and select allergic, atopic, immune-mediated mental health and bone health conditions and skin infections was identified. There is some evidence supporting an association between AD and substance use, attention deficit hyperactivity disorder, and elements of metabolic syndrome. Evidence suggests a small association with various cardiovascular conditions. The association between AD in adults and autism spectrum disorders, myocardial infarction, stroke, and metabolic syndrome is inconclusive. Limitations: This analysis is based on the best available evidence at the time it was conducted. This guideline does not make recommendations for screening or management of comorbidities in adults with AD. Conclusions: Clinicians should be aware of comorbidities associated with AD. Further research is needed to determine whether screening or management of comorbidities is beneficial for adults with AD.

引用

页码：1335 / 1336.e18

页数：18

共 179 条

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