Chemical compositions and biological activities of leaf essential oils of twelve species of Piper from Monteverde, Costa Rica

被引：0

作者：

Setzer, William N. ^{[1
]}

Park, Grace ^{[1
]}

Agius, Brittany R. ^{[1
]}

Stokes, Sean L. ^{[1
]}

Walker, Tameka M. ^{[1
]}

Haber, William A. ^{[2
]}

机构：

[1] Univ Alabama, Dept Chem, Huntsville, AL 35899 USA

[2] Missouri Bot Garden, St Louis, MO 63166 USA

来源：

NATURAL PRODUCT COMMUNICATIONS | 2008年 / 3卷 / 08期

关键词：

Piper; essential oil; composition; bioactivity; cluster analysis;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The leaf essential oils of twelve species of Piper (Piperaceae) from Monteverde, Costa Rica (Piper aequale, Piper amalago, Piper biasperatum, Piper bredemeyeri, Piper dotanum, Piper fimbriulatum, Piper glabrescens, Piper imperiale, Piper lanceifolium, Piper nemorense, Piper oblanceolatum, and Piper sp. A near aereum) have been obtained by hydrodistillation and analyzed by GC-MS. The Piper leaf oils have been screened for antibacterial activity against Bacillus cereus, Staphylococcus aureus, and Escherichia coli; for Artemia salina (brine shrimp) lethality; for in-vitro cytotoxic activity against C, MCF-7 (human breast tumor) cells; and inhibition of the cysteine protease cruzain. A cluster analysis comparison with previously published Piper leaf oil compositions was carried out in order to discern the differences and similarities between the volatile chemical compositions of Piper species.

引用

页码：1367 / 1374

页数：8

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