The effect of overactive bladder treatment with anticholinergics on female sexual function in women: a prospective observational study

PurposeThe aim of the study was to determine the effect of anticholinergics used for overactive bladder treatment on the sexual function of women.MethodsBetween January 2016 and August 2018, over 18years old, 216 sexual active women with OAB and 165 healthy women as control group were prospectively enrolled in the study. Five different anticholinergics were used for the treatment. Female Sexual Function Index (FSFI), eight-item overactive bladder awareness tool (OAB-V8), and Beck Depression Inventory form were completed before and after 3months. Baseline and post-treatment scores were compared with a control group of age-matched healthy women.ResultsPatients with OAB reported at baseline significantly worse sexual function in all FSFI domains compared to healthy control group (21.473.22 vs. 26.79 +/- 5.56, p<0.01). Three months after treatment, over 85% of participants reported clinically relevant improvements in sexual function, with statistically significant changes in mean FSFI scores.Conclusions p id=Par4 Treatment of OAB with anticholinergics can improve sexual function of sexual active women with OAB. Patients may be informed about this potential benefit of anticholinergic treatment, to improve their sexual function.