Pathogens and polymers: Microbe-host interactions illuminate the cytoskeleton

被引：154

作者：

Haglund, Cat M. ^{[1
]}

Welch, Matthew D. ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

来源：

JOURNAL OF CELL BIOLOGY | 2011年 / 195卷 / 01期

关键词：

ACTIN-BASED MOTILITY; CELL-TO-CELL; SALMONELLA-CONTAINING VACUOLES; FILAMENT BARBED ENDS; LISTERIA-MONOCYTOGENES; ARP2/3; COMPLEX; N-WASP; SHIGELLA-FLEXNERI; INTERMEDIATE-FILAMENTS; BACTERIAL INTERNALIZATION;

D O I：

10.1083/jcb.201103148

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Intracellular pathogens subvert the host cell cytoskeleton to promote their own survival, replication, and dissemination. Study of these microbes has led to many discoveries about host cell biology, including the identification of cytoskeletal proteins, regulatory pathways, and mechanisms of cytoskeletal function. Actin is a common target of bacterial pathogens, but recent work also highlights the use of microtubules, cytoskeletal motors, intermediate filaments, and septins. The study of pathogen interactions with the cytoskeleton has illuminated key cellular processes such as phagocytosis, macropinocytosis, membrane trafficking, motility, autophagy, and signal transduction.

引用

页码：7 / 17

页数：11

共 126 条

[1] Salmonella enterica Serovar Typhimurium Invades Fibroblasts by Multiple Routes Differing from the Entry into Epithelial Cells [J].

Aiastui, Ana ;

Graciela Pucciarelli, M. ;

Garcia-del Portillo, Francisco .

INFECTION AND IMMUNITY, 2010, 78 (06) :2700-2713

[2] Salmonella-Containing Vacuoles: Directing Traffic and Nesting to Grow [J].

Bakowski, Malina A. ;

Braun, Virginie ;

Brumell, John H. .

TRAFFIC, 2008, 9 (12) :2022-2031

[3] Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton [J].

Barda-Saad, M ;

Braiman, A ;

Titerence, R ;

Bunnell, SC ;

Barr, VA ;

Samelson, LE .

NATURE IMMUNOLOGY, 2005, 6 (01) :80-89

[4] Actin machinery: pushing the envelope [J].

Borisy, GG ;

Svitkina, TM .

CURRENT OPINION IN CELL BIOLOGY, 2000, 12 (01) :104-112

[5] The intracellular fate of Salmonella depends on the recruitment of kinesin [J].

Boucrot, E ;

Henry, T ;

Borg, JP ;

Gorvel, JP ;

Méresse, S .

SCIENCE, 2005, 308 (5725) :1174-1178

[6] How do in vitro reconstituted actin-based motility assays provide insight into in vivo behavior? [J].

Bugyi, Beata ;

Le Clainche, Christophe ;

Romet-Lemonne, Guillaume ;

Carlier, Marie-France .

FEBS LETTERS, 2008, 582 (14) :2086-2092

[7] Cytoskeleton-modulating effectors of enteropathogenic and enterohaemorrhagic Escherichia coli: Tir, EspFU and actin pedestal assembly [J].

Campellone, Kenneth G. .

FEBS JOURNAL, 2010, 277 (11) :2390-2402

[8] Repetitive N-WASP-Binding Elements of the Enterohemorrhagic Escherichia coli Effector EspFU Synergistically Activate Actin Assembly [J].

Campellone, Kenneth G. ;

Cheng, Hui-Chun ;

Robbins, Douglas ;

Siripala, Anosha D. ;

McGhie, Emma J. ;

Hayward, Richard D. ;

Welch, Matthew D. ;

Rosen, Michael K. ;

Koronakis, Vassilis ;

Leong, John M. .

PLOS PATHOGENS, 2008, 4 (10)

[9] GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex [J].

Carlier, MF ;

Nioche, P ;

Broutin-L'Hermite, I ;

Boujemaa, R ;

Le Clainche, C ;

Egile, C ;

Garbay, C ;

Ducruix, A ;

Sansonetti, P ;

Pantaloni, D .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (29) :21946-21952

[10] Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation [J].

Castellano, F ;

Montcourrier, P ;

Guillemot, JC ;

Gouin, E ;

Machesky, L ;

Cossart, P ;

Chavrier, P .

CURRENT BIOLOGY, 1999, 9 (07) :351-360

← 1 2 3 4 5 6 7 8 9 10 →