Risk-oriented concept of treatment for intrathyroid papillary thyroid cancer

被引：12

作者：

Hartl, Dana M. ^{[1
]}

Hadoux, Julien ^{[2
]}

Guerlain, Joanne ^{[1
]}

Breuskin, Ingrid ^{[1
]}

Haroun, Fabienne ^{[1
]}

Bidault, Sophie ^{[3
]}

Leboulleux, Sophie ^{[2
]}

Lamartina, Livia ^{[2
]}

机构：

[1] Gustave Roussy, Thyroid Surg Unit, Dept Head & Neck Oncol, 114 Rue Edouard Vaillant, F-94805 Villejuif, France

[2] Gustave Roussy, Nucl Med & Endocrine Oncol, 114 Rue Edouard Vaillant, F-94805 Villejuif, France

[3] Gustave Roussy, Dept Radiol, 114 Rue Edouard Vaillant, F-94805 Villejuif, France

来源：

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM | 2019年 / 33卷 / 04期

关键词：

thyroid cancer; dynamic risk assessment; active surveillance; CENTRAL NECK DISSECTION; LYMPH-NODE DISSECTION; ACTIVE SURVEILLANCE; RADIOACTIVE IODINE; COST-EFFECTIVENESS; LOCOREGIONAL RECURRENCE; CLINICAL-IMPLICATIONS; RADIOIODINE ABLATION; DOSE RADIOIODINE; REMNANT ABLATION;

D O I：

10.1016/j.beem.2019.05.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Adapting treatment and follow-up according to the risk of recurrence and/or death from thyroid cancer is a relatively recent concept of "personnalized" medicine, developed particularly to avoid overtreatment of low-risk thyroid cancer which represents the majority of thyroid cancers diagnosed in the world today. For low-risk thyroid cancer, this decrease in extent of treatment involves the extent of surgery-total thyroidectomy, lobectomy or no surgery with active surveillance-but also the indications, doses and methods of stimulation when or if administering radioactive iodine (RAI), the indication for suppressive thyroxin therapy and the extent and modalities for follow-up that should be adapted to the risk of recurrence. The aim is to optimize medical resources and quality of life, particularly for low-risk patients whose life expectancy is that of the general population. (C) 2019 Published by Elsevier Ltd.

引用

页数：16

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