Giant gastrointestinal stromal tumor with predominantly cystic changes: a case report and literature review

被引：14

作者：

Wang, Liying ^{[1
]}

Liu, Libin ^{[1
]}

Liu, Zhaohui ^{[1
]}

Tian, Yueli ^{[1
]}

Lin, Zhe ^{[2
]}

机构：

[1] Jilin Univ, Hosp 2, Dept Gastroenterol, 218 Ziqiang St, Changchun 130042, Jilin, Peoples R China

[2] Jilin Univ, Hosp 2, Dept Gastrointestinal Nutr & Hernia Surg, Changchun, Jilin, Peoples R China

来源：

WORLD JOURNAL OF SURGICAL ONCOLOGY | 2017年 / 15卷

关键词：

Gastrointestinal stromal tumor; Stomach; Cyst; Diagnosis; PATHOLOGICAL CORRELATION; STOMACH; GIST;

D O I：

10.1186/s12957-017-1285-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Gastrointestinal stromal tumors (GISTs) rarely present with predominantly cystic changes. Here, we report a case of giant GIST of the stomach with predominantly cystic changes in a 74-year-old female patient. Case presentation: The tumor was 10 cm x 15 cm in size and positive for CD117, H-caldesmon, and DOG-1. Complete surgical resection was performed without regional lymphadenectomy. The patient recovered uneventfully and no recurrence occurred. Conclusions: The case illustrates that GIST with cystic changes should be considered in the diagnoses of hepatic and pancreatic lesions. Furthermore, immunohistochemistry with CD117, DOG1, and other molecular markers is critical for diagnosis of GIST of the stomach and facilitates optimization of treatments for GIST.

引用

页数：4

共 15 条

[1]

[陈新岐 Chen Xinqi], 2013, [中华消化外科杂志, Chinese Journal of Digestive Surgery], V12, P475

[2] Malignant stromal tumor of the stomach with giant cystic liver metastases prior to treatment with imatinib mesylate [J].

Colovic, Radoje ;

Micev, Marjan ;

Matic, Slavko ;

Colovic, Natasa ;

Grubor, Nikica ;

Atkinson, Henry Dushan .

VOJNOSANITETSKI PREGLED, 2013, 70 (02) :225-228

[3] Spontaneous intratumoral bleeding and rupture of giant gastric stromal tumor (> 30 cm) in a young patient [J].

Cruz, Ruy J., Jr. ;

Vincenzi, Rodrigo ;

Ketzer, Bernardo M. ;

Cecilio, Andre L. ;

Cepeda, Lourdes A. .

WORLD JOURNAL OF SURGICAL ONCOLOGY, 2008, 6 (1)

[4] From the archives of the AFIP - Gastrointestinal stromal tumors: Radiologic features with pathologic correlation [J].

Levy, AD ;

Remotti, HE ;

Thompson, WM ;

Sobin, LH ;

Miettinen, M .

RADIOGRAPHICS, 2003, 23 (02) :283-304

[5]

Miettinen M, 2006, ARCH PATHOL LAB MED, V130, P1466

[6]

Notani Hiroyuki, 2013, Gan To Kagaku Ryoho, V40, P2179

[7] A case of a stomach gastrointestinal stromal tumor with extremely predominant cystic formation [J].

Okano H. ;

Tochio T. ;

Suga D. ;

Kumazawa H. ;

Isono Y. ;

Tanaka H. ;

Matsusaki S. ;

Sase T. ;

Saito T. ;

Mukai K. ;

Nishimura A. ;

Baba Y. ;

Murata T. .

Clinical Journal of Gastroenterology, 2015, 8 (4) :197-201

[8] Gastrointestinal stromal tumor of the stomach with a giant abscess penetrating the gastric lumen [J].

Osada, Taro ;

Nagahara, Akihito ;

Kodani, Tomohiro ;

Namihisa, Akihiro ;

Kawabe, Masato ;

Yoshizawa, Takashi ;

Ohkusa, Toshifurni ;

Watanabe, Sumio .

WORLD JOURNAL OF GASTROENTEROLOGY, 2007, 13 (16) :2385-2387

[9] Multifocal gastrointestinal stromal tumor (GIST) of the stomach in an 11-year-old girl [J].

Park, Jin ;

Rubinas, Tara C. ;

Fordham, Lynn Ansley ;

Phillips, J. Duncan .

PEDIATRIC RADIOLOGY, 2006, 36 (11) :1212-1214

[10] Gastrointestinal stromal tumor (GIST) mistaken for pancreatic pseudocyst - case report and literature review [J].

Pereira Hansen, Cristiano de Assis ;

Jose, Fabio Freire ;

Engracia Garcia Caluz, Naiara Pedrassi .

CLINICAL CASE REPORTS, 2014, 2 (05) :197-200

← 1 2 →