SLEEP QUALITY MEDIATES THE RELATIONSHIP BETWEEN RISK OF OBSTRUCTIVE SLEEP APNEA AND ACUTE STRESS IN YOUNG ADULTS

Intermittent hypoxia and transient arousals in obstructive sleep apnea (OSA) can lead to poor sleep quality and acute stress. Rising levels of obesity and increased incidence of OSA in young adults predisposes them to acute stress. We propose a mediation model to assess if risk of OSA is associated with acute stress and if the relationship between risk for OSA and acute stress is mediated by sleep quality. 493 healthy individuals (F = 237, M = 256) from 18 - 25 years of age (mean age 20.3 +/- 1.53 years) were screened for OSA, sleep quality and acute stress using STOP-BANG questionnaire, Pittsburg Sleep Quality Index and American Psychiatry Association's National Stressful Events Survey Acute Stress Disorder Short Scale (NSESS-S), respectively. 73 participants (17.3%) were found at an intermediate and high risk of OSA by STOP BANG questionnaire. 79 (16%) participants reported level of stress as 'None'. Mild, moderate and severe stress was present in 248 (50.3%), 109 (22.1%), 51 (10.3%) and 16 (3.2%) participants, respectively. The odds of having severe and extreme stress among those at risk of sleep apnea is 2.18 times higher than that among those not at risk of sleep apnea (OR: 2.18, 95%, confidence interval: 1.37-3.51). Sobel test established that the relationship between OSA and acute stress is mediated by sleep quality. Sleep quality mediates the relationship between risk for sleep apnea and acute stress. This highlights the importance of screening for OSA in young adults, particularly young men with high BMI, presenting with high stress levels.