Body composition and body mass index in Duchenne muscular dystrophy: Role of dietary intake

被引：22

作者：

Bernabe-Garcia, Mariela ^{[1
]}

Rodriguez-Cruz, Maricela ^{[2
]}

Atilano, Salvador ^{[2
]}

del Rocio Cruz-Guzman, Oriana ^{[2
]}

Almeida-Becerril, Tomas ^{[2
]}

Calder, Philip C. ^{[3
,4
,5
]}

Gonzalez, Julia ^{[2
]}

机构：

[1] Hosp Pediat Mexico City, Ctr Med Nacl Siglo 21, Inst Mexicano Seguro Social, Unidad Invest Med Nutr, Ave Cuauhtemoc 330, Mexico City 06725, DF, Mexico

[2] Hosp Pediat Mexico City, Ctr Med Nacl Siglo 21, Inst Mexicano Seguro Social, Lab Nutr Mol,Unidad Invest Med Nutr, Mexico City, DF, Mexico

[3] Univ Southampton, Fac Med, Human Dev & Hlth Acad Unit, Southampton, Hants, England

[4] Univ Hosp Southampton NHS Fdn Trust, NIHR Southampton Biomed Res Ctr, Southampton, Hants, England

[5] Univ Southampton, Southampton, Hants, England

来源：

MUSCLE & NERVE | 2019年 / 59卷 / 03期

关键词：

body composition; body mass index; dietary intake; Duchenne muscular dystrophy; obesity; pediatric patients; CHILD GROWTH STANDARDS; X-RAY ABSORPTIOMETRY; ENERGY-EXPENDITURE; NUTRITION; WEIGHT; ADOLESCENTS; OVERWEIGHT; DIAGNOSIS; POSITION; ATROPHY;

D O I：

10.1002/mus.26340

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction: In Duchenne muscular dystrophy (DMD) muscle is replaced by adipose tissue. The role of dietary intake (DI) in DMD has not been evaluated. In this study we examined body composition, body mass index (BMI), and adequacy of DI in patients with DMD and evaluated the influence of DI on body composition. Methods: Patients (n = 101; age 3-18 years; BMI 11.8-29.5 kg/m(2)) completed a dietary recall to determine DI and then underwent dual-energy X-ray absorptiometry to determine body composition. Results: Preschool-age and school-age boys with DMD had high total energy intake. Protein intake per kilogram exceeded recommendations. As age increased, the percentage of boys with abnormal BMI and fat mass increased, while lean mass decreased. Dietary intake did not predict body fat or lean mass. Discussion: Age-dependent changes in BD in boys with DMD may be due to endogenous metabolic factors related to the underlying disease process and to disease-related mobility impairments. Muscle Nerve 59:295-302, 2019

引用

页码：295 / 302

页数：8

共 45 条

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