FLAVONOIDS AND OTHER BIOACTIVE PHENOLICS ISOLATED FROM Cenostigma macrophyllum (LEGUMINOSAE)

被引：22

作者：

Alves, Clayton Q. ^{[1
]}

David, Jorge M. ^{[1
]}

David, Juceni P. ^{[2
]}

Villareal, Cristiane F. ^{[2
]}

Soares, Milena B. P. ^{[3
]}

de Queiroz, Luciano P. ^{[4
]}

Aguiar, Rosane M. ^{[5
]}

机构：

[1] Univ Fed Bahia, Inst Quim, BR-40170280 Salvador, BA, Brazil

[2] Univ Fed Bahia, Fac Farm, BR-40170280 Salvador, BA, Brazil

[3] Fundacao Oswaldo Cruz, Ctr Pesquisas Goncalo Moniz, BR-40029500 Salvador, BA, Brazil

[4] Univ Estadual Feira de Santana, Dept Ciencias Biol, BR-44031460 Feira De Santana, BA, Brazil

[5] Univ Estadual Sudoeste Bahia, Dept Quim & Exatas, Jequie, BA, Brazil

来源：

QUIMICA NOVA | 2012年 / 35卷 / 06期

关键词：

Cenostigma macrophyllum; Cenostigma gardnerianum; antinociceptive activity; ANTIOXIDANT ACTIVITY; CONSTITUENTS; GLYCOSIDES;

D O I：

10.1590/S0100-40422012000600013

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This work describes the phytochemical study of stem bark and leaves of Cenostigma macrophyllum Tul. (Leguminosae). Through usual chromatographic techniques were isolated bergenin as the primary compound of the stem bark of and from the leaves gallic acid, methyl gallate, ellagic acid, quercetin, quercetin-3-O-beta-D glucopyranoside, quercetin-3-O-(6 ''-O-galloyl)-beta-D-glucopyranoside (tellimoside), quercetin-3-O-(6 ''-O-E-p-coumaroyl)-beta-D-glucopyranoside (helichrysroside), agathisflavone and vitexin were obtained. The isolates were identified by spectroscopic data analysis, and bergenin showed dose-related antinociception when assessed in acetic acid-induced writhing in mice.

引用

页码：1137 / 1140

页数：4

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