Allylations of chelated enolates using dienyl substrates

被引：9

作者：

Basak, Sankar ^{[1
]}

Kazmaier, Uli ^{[1
]}

机构：

[1] Univ Saarland, Inst Organ Chem, D-66123 Saarbrucken, Germany

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 03期

关键词：

D O I：

10.1021/ol702865q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Isomerization-free reactions of dienyl carbonates (1-3) with chelated amino acid ester enolates at -78 degrees C provide important information concerning the mechanism of these dienylations. The formation of regioisomeric products can be explained by competing S(N)2/S(N)2' reactions, and the product distribution can be influenced by proper choice of the reaction conditions.

引用

页码：501 / 504

页数：4

共 69 条

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