Allylations of chelated enolates using dienyl substrates

被引：9
作者：
Basak, Sankar [1 ]
Kazmaier, Uli [1 ]
机构：
[1] Univ Saarland, Inst Organ Chem, D-66123 Saarbrucken, Germany
来源：
ORGANIC LETTERS | 2008年 / 10卷 / 03期
关键词：
D O I：
10.1021/ol702865q
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Isomerization-free reactions of dienyl carbonates (1-3) with chelated amino acid ester enolates at -78 degrees C provide important information concerning the mechanism of these dienylations. The formation of regioisomeric products can be explained by competing S(N)2/S(N)2' reactions, and the product distribution can be influenced by proper choice of the reaction conditions.
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页码：501 / 504
页数：4
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