Asymmetric synthesis of anti-convulsive drug (S)-Vigabatrin®

被引：27
|
作者：
Chandrasekhar, S [1 ]
Mohapatra, S [1 ]
机构：
[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 35期
关键词：
D O I：
10.1016/S0040-4039(98)01324-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An asymmetric synthesis of fully protected (S) - Vigabatrin(R) is described using Sharpless asymmetric aminohydroxylation and reductive elimination of alpha-oxy-beta-amino carbonylhydrazone as key steps. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：6415 / 6418
页数：4
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