Robot assisted radical cystectomy with totally intracorporeal urinary diversion: initial, single-surgeon's experience after a modified modular training

被引:35
作者
Porreca, Angelo [1 ]
Chessa, Francesco [2 ]
Romagnoli, Danicle [2 ]
Salvaggio, Antonio [1 ]
Cafarelli, Angelo [1 ]
Borghesi, Marco [2 ]
Bianchi, Lorenzo [2 ]
Dandrea, Matteo [1 ]
D'Agostini, Daniele [1 ]
Dente, Donato [1 ]
Cappa, Emanuele [1 ]
Wiklund, Peter [3 ]
Brunocilla, Eugenio [2 ]
Schiavina, Riccardo [2 ]
机构
[1] Policlin Di Abano, Dept Urol, Padua, Italy
[2] Univ Bologna, S Orsola Malpighi Hosp, Dept Urol, Via Palagi 9, Bologna, Italy
[3] Karolinska Inst, Dept Urol, Stockholm, Sweden
关键词
Robotics; Cystectomy; Learning curve; Outcome assessment; health care; BLADDER-CANCER; LEARNING-CURVE; COMPLICATIONS; OUTCOMES; CONSORTIUM; NEOBLADDER; VOLUME; RISK;
D O I
10.23736/S0393-2249.17.02970-8
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND: To report the perioperative and early functional outcomes of patients undergoing Robot-assisted radical cystectomy (RARC) with totally intracorporeal urinary diversion performed by a single surgeon after a modified modular training. METHODS: The surgeon (A.P.) attained a 30-days modified modular training at a referring Center mentored by a worldwide-recognized robotic surgeon (P.W.). The training program consisted of: 1) e-learning based on 10 hours of theoretical lessons made by the mentor, 2) video-session concerning the different steps of the procedure, 3) step-by-step in vivo modular training. Demographics, intraoperative data and post-operative complications were recorded for each patient. RESULTS: Twenty-four consecutive patients were prospectively evaluated. Median age was 68.5 years (IQR 59-75). Thirteen (54.2%) and 11 (45.8%) patients received RARC with orthotopic neobladder (ONB) and ilcal conduit (IC), respectively. Overall mean (+/- SD) operative time was 392 (I: 34.8) minutes. The median number of lymph node retrieved was 30 (IQR 24-42), the mean intraoperative estimated blood loss (EBL) was 403 mL (+/- 60) with average hospitalization of 7.8 days (+/- 2.2). All procedures were completed successfully without open conversion. A statistically significant difference in tenns of overall operative time (OT) and urinary diversion operative time (UDOT) was found in favor of IC group compared to ONB group (P=0.002). Overall complication rate was 33%, 7 out of 9 (88%) were graded as minor (Clavien 1-2). Two (22%) major complications (Clavien 3-5) occurred solely on ONB group. CONCLUSIONS: Robot-assisted radical cystectomy with totally intracorporeal urinary diversion is a challenging procedure with a steep learning curve. An adequate modular training with an experienced mentor and a skilled robotic team could be essential to reach these optimal results. Further studies investigating the impact of modular learning curve and a dedicated menthorship on operative and functional outcomes after RARC are needed.
引用
收藏
页码:193 / 201
页数:9
相关论文
共 29 条
[1]   Health-related Quality of Life Outcomes After Robot-assisted and Open Radical Cystectomy Using a Validated Bladder-specific Instrument: A Multi-institutional Study [J].
Aboumohamed, Ahmed A. ;
Raza, Syed Johar ;
Al-Daghmin, Ali ;
Tallman, Christopher ;
Creighton, Terrance ;
Crossley, Heather ;
Dailey, Stephen ;
Khan, Aabroo ;
Din, Rakeeba ;
Mehedint, Diana ;
Wang, Katy ;
Shi, Yi ;
Sharif, Mohamed ;
Wilding, Gregory ;
Weizer, Alon ;
Guru, Khurshid A. .
UROLOGY, 2014, 83 (06) :1300-1308
[2]  
[Anonymous], 2002, AJCC cancer staging manual, V6th, P157
[3]   Comparing Open Radical Cystectomy and Robot-assisted Laparoscopic Radical Cystectomy: A Randomized Clinical Trial [J].
Bochner, Bernard H. ;
Dalbagni, Guido ;
Sjoberg, Daniel D. ;
Silberstein, Jonathan ;
Paz, Gal E. Keren ;
Donat, S. Machele ;
Coleman, Jonathan A. ;
Mathew, Sheila ;
Vickers, Andrew ;
Schnorr, Geoffrey C. ;
Feuerstein, Michael A. ;
Rapkin, Bruce ;
Parra, Raul O. ;
Herr, Harry W. ;
Laudone, Vincent P. .
EUROPEAN UROLOGY, 2015, 67 (06) :1042-1050
[4]   Small Renal Masses Initially Managed Using Active Surveillance: Results From a Retrospective Study With Long-Term Follow-Up [J].
Brunocilla, Eugenio ;
Borghesi, Marco ;
Schiavina, Riccardo ;
Della Mora, Livia ;
Dababneh, Hussam ;
La Manna, Gaetano ;
Monti, Carlo ;
Martorana, Giuseppe .
CLINICAL GENITOURINARY CANCER, 2014, 12 (03) :178-181
[5]   Epidemiology and Risk Factors of Urothelial Bladder Cancer [J].
Burger, Maximilian ;
Catto, James W. F. ;
Dalbagni, Guido ;
Grossman, H. Barton ;
Herr, Harry ;
Karakiewicz, Pierre ;
Kassouf, Wassim ;
Kiemeney, Lambertus A. ;
La Vecchia, Carlo ;
Shariat, Shahrokh ;
Lotan, Yair .
EUROPEAN UROLOGY, 2013, 63 (02) :234-241
[6]   The Clavien-Dindo Classification of Surgical Complications Five-Year Experience [J].
Clavien, Pierre A. ;
Barkun, Jeffrey ;
de Oliveira, Michelle L. ;
Vauthey, Jean Nicolas ;
Dindo, Daniel ;
Schulick, Richard D. ;
de Santibanes, Eduardo ;
Pekolj, Juan ;
Slankamenac, Ksenija ;
Bassi, Claudio ;
Graf, Rolf ;
Vonlanthen, Rene ;
Padbury, Robert ;
Cameron, John L. ;
Makuuchi, Masatoshi .
ANNALS OF SURGERY, 2009, 250 (02) :187-196
[7]   Robot-assisted radical cystectomy (RARC) with intracorporeal neobladder - what is the effect of the learning curve on outcomes? [J].
Collins, Justin W. ;
Tyritzis, Stavros ;
Nyberg, Tommy ;
Schumacher, Martin C. ;
Laurin, Oscar ;
Adding, Christofer ;
Jonsson, Martin ;
Khazaeli, Dinyar ;
Steineck, Gunnar ;
Wiklund, Peter ;
Hosseini, Abolfazl .
BJU INTERNATIONAL, 2014, 113 (01) :100-107
[8]   Robot-assisted Radical Cystectomy: Description of an Evolved Approach to Radical Cystectomy [J].
Collins, Justin W. ;
Tyritzis, Stavros ;
Nyberg, Tommy ;
Schumacher, Martin ;
Laurin, Oscar ;
Khazaeli, Dinyar ;
Adding, Christofer ;
Jonsson, Martin N. ;
Hosseini, Abolfazl ;
Wiklund, N. Peter .
EUROPEAN UROLOGY, 2013, 64 (04) :654-663
[9]   Perioperative and oncologic outcomes of robot-assisted vs. open radical cystectomy in bladder cancer patients: A comparison of two high-volume referral centers [J].
Gandaglia, G. ;
Karl, A. ;
Novara, G. ;
de Groote, R. ;
Buchner, A. ;
D'Hondt, F. ;
Montorsi, F. ;
Stief, C. ;
Mottrie, A. ;
Gratzke, C. .
EJSO, 2016, 42 (11) :1736-1743
[10]   Radical cystectomy for carcinoma of the bladder: 2,720 consecutive cases 5 years later [J].
Ghoneim, Mohamed A. ;
Abdel-Latif, Mohamed ;
El-Mekresh, Mohsen ;
Abol-Enein, Hassan ;
Mosbah, Ahmed ;
Ashamallah, Albair ;
El-Baz, Mahmoud A. .
JOURNAL OF UROLOGY, 2008, 180 (01) :121-127